Herbicidal sulfonamides

ABSTRACT

This invention relates to certain sulfonylurea compounds having substituents ortho to the sulfonylurea linkage that includes a 3- or 4- membered carbocyclic ring, a saturated 5- or 6- membered carbocyclic ring or a heterocyclic ring which contains 1 heteroatom selected from O, S and NR3, agriculturally suitable compositions thereof and a method of their use as herbicides or plant growth regulants.

RELATED APPLICATIONS

This is a division of application U.S. Ser. No. 769,691 filed Aug. 29, 1985, now U.S. Pat. No 4,666,501, which is a continuation-in-part of application U.S. Ser. No. 680,549 filed Dec. 11, 1984, now abandoned.

BACKGROUND OF THE INVENTION

This invention relates to herbicidally active sulfonylurea compounds, agriculturally suitable compositions containing them and their method of use as herbicides or plant growth regulants.

In the most common situation, the control of undesired vegetation is desired to permit the growth of useful crops such as cotton, rice, corn, wheat and soybeans, to name a few. Unchecked weed growth in such useful crops can cause significant losses, reducing profit to the farmer and increasing costs to the consumer. In other situations, herbicides are desired which will control all plant growth. Examples of areas in which complete control of all vegetation is desired are areas around fuel storage tanks, ammunition depots and industrial storage areas. There are many products commercially available for these purposes, but the search continues for products which are more effective, less costly and environmentally safe.

European Patent Application (EP-A) No. 83,975, published July 20, 1983, discloses herbicidal benzenesulfonamides of formula ##STR1## wherein Q is selected from various five or six-membered aromatic or partially unsaturated heterocyclic rings containing 2 or 3 heteroatoms selected from O, S or NR.

U.S. Pat. No. 4,368,069 discloses herbicidal benzenesulfonamides of formula ##STR2## wherein R is --(CR₅ R₆)_(n) --R₂ ;

n is 0 or 1; and

R₂ may be C₂ -C₅ alkenyl, C₅ -C₆ cycloalkenyl or C₂ -C₃ alkenyl substituted with 1-3 chlorine atoms.

European Patent Application (EP-A) No. 85,476, published Aug. 10, 1983, discloses herbicidal benzenesulfonamides of formulae ##STR3## wherein Q is selected from various 5-membered aromatic heterocycles, and their dihydro and tetrahydro analogs, which contain one heteroatom selected from O, S or NR, or Q is a saturated or partially unsaturated 6-membered ring containing one heteroatom selected from O or S; and

Q¹ is a 6-membered aromatic heterocycle containing one to three N atoms.

South African Patent Application No. 83/8416, published May, 1984, discloses herbicidal benzenesulfonamides of formula ##STR4## wherein A is an unsaturated or only partially saturated 5- or 6-membered heterocyclic ring system which is bonded through a carbon atom and contains 1, 2 or 3 heteroatoms.

Herbicidal thiophene sulfonamides are disclosed in European Patent Application (EP-A) Nos. 30,142, published June 10, 1981, and 97,122, published Dec. 28, 1983, and in U.S. Pat. Nos. 4,127,405, 4,169,719, 4,398,939 and 4,441,910.

EP-A-95,925, published Dec. 7, 1983, discloses herbicidal pyrazolesulfonamides in which the group adjacent to the sulfonamide moiety may be selected from H, C₁ -C₃ alkyl, F, Cl, Br, NO₂, OR₁₆, CO₂ R₂₃, S(O)_(n) R₂₄ or SO₂ NR₁₉ R₂₀.

EP-A-87,780, published Sept. 7, 1983 discloses pyrazole sulfonamides of general formula ##STR5## wherein A is H, C₁ -C₈ alkyl or optionally substituted phenyl;

B and C are independently H, halogen, NO₂, C₁ -C₈ alkyl, CO₂ R, etc.; and

D is H or C₁ -C₈ alkyl.

EP-A-96,003, published Nov. 28, 1983, discloses herbicidal compounds of general formula ##STR6## wherein R₁ is H or C₁ -C₃ alkyl; and

Q is an unsubstituted or substituted five-membered heterocyclic radical which is bound by way of a carbon atom and which contains 2 or 3 identical or different heteroatoms.

Herbicidal pyridinesulfonamides are disclosed in European Patent Application Nos. 13,480 published July 23, 1980, 35,893 published Sept. 16, 1981, 97,122 published Dec. 28, 1983 and 103,543 published Mar. 21, 1984 and in U.S. Pat. No. 4,435,206.

U.S. Pat. No. 4,420,325 discloses herbicidal sulfonamides of the following formula ##STR7## wherein R₁ is F, Cl, Br, CF₃, C₁ -C₃ alkoxy, C₁ -C₃ alkyl, NO₂, CO₂ R₄, SO₂ R₅, SO₂ NR₆ R₇, SO₂ N(OCH₃)CH₃, SO₂ OCH₂ CF₃, OSO₂ R₅ or CH₂ L;

R₂ is H, Cl, Br, F, CF₃ or OCH₃ ;

R₉ is H or C₁ -C₃ alkyl; etc.

SUMMARY OF THE INVENTION

This invention is the discovery of new compounds with herbicidal activity, agriculturally suitable compositions thereof and a method of using said compounds as general or selective preemergent and/or post emergent herbicides. Accordingly the new compounds of the invention are compounds of the formula ##STR8## wherein W is O or s;

R is H or CH₃ ;

L is ##STR9## n is 0 or 1; R₁ is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, nitro, CN, C₁ -C₃ alkoxy, SO₂ NR^(I) R^(II), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, CO₂ R^(III), CH₂ CN, CH₂ OCH₃ or CH₂ SCH₃ ;

R^(I) is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy or ethoxy;

R^(II) is H, C₁ -C₄ alkyl or C₃ -C₄ alkenyl; or

R^(I) and R^(II) may be taken together as --(CH₂)₃ --, --(CH₂)₄ --, --(CH₂)₅ -- or --CH₂ CH₂ OCH₂ CH₂ --;

R^(III) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₃ cyanoalkyl, C₅ -C₆ cycloalkyl, C₄ -C₇ cycloalkylalkyl or C₂ -C₄ alkoxyalkyl;

R₂ is C₁ -C₃ alkyl;

Q is a 3- or 4-membered heterocyclic ring which contains one heteroatom selected from O, S and NR₃, or a 3- or 4-membered carbocyclic ring in which one carbon atom may optionally be in the form of a carbonyl group, or a fully-saturated 5- or 6-membered carbocyclic ring, and Q may be optionally substituted with 1-4 substituents selected from halogen, CN, OH, C₁ -C₃ alkyl, C₁ -C₃ alkoxy, C₁ -C₃ alkylthio, C₂ -C₄ alkoxycarbonyl, C₁ -C₄ alkylsulfonyl, (C₁ -C₄ alkyl)-aminosulfamoyl and di(C₁ -C₄ alkyl)aminosulfamoyl;

R₃ is C₁ -C₄ alkyl;

R₁₂ is H or OR₁₄ ;

R₁₃ is H or C₁ -C₄ alkyl;

R₁₄ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ haloalkenyl, C₃ -C₄ alkynyl, C₃ -C₄ haloalkynyl, C₂ -C₄ alkylcarbonyl, C(O)NR₁₅ R₁₆, C₁ -C₄ alkylsulfonyl, C₂ -C₄ alkoxyalkyl or C₂ -C₄ alkylthioalkyl;

R₁₅ and R₁₆ are independently H or C₁ -C₂ alkyl;

A is ##STR10## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃ alkyl)amino;

Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₃ -C₅ cycloalkyl, C₂ -C₄ alkynyl, ##STR11## or N(OCH₃)CH₃ ; m is 2 or 3;

L₁ and L₂ are independently O or S;

R₄ and R₅ are independently C₁ -C₂ alkyl;

R₆ is H or CH₃ ;

Z is CH or N;

Y₁ is O or CH₂ ;

X₁ is CH₃, OCH₃, OC₂ H₅ or OCF₂ H;

Y₂ is H or CH₃ ;

X₂ is CH₃, OCH₃ or SCH₃ ;

Y₃ is CH₃, CH₂ CH₃ or CH₂ CF₃ ;

X₃ is CH₃ or OCH₃ ;

Y₄ is CH₃, OCH₃, OC₂ H₅ or Cl; and

X₄ is CH₃, OCH₃, OC₂ H.sub. or CH₂ OCH₃ ;

and their agriculturally suitable salts; provided that

(a) when X is Cl, F, Br or I, then Z is CH and Y is OCH₃, OC₂ H₅, N(OCH₃)CH₃, NHCH₃, N(CH₃)₂ or OCF₂ H;

(b) when X or Y is OCF₂ H, then Z is CH;

(c) when L is L-2 or L-3, then the Q substituent and the sulfonylurea bridge are on adjacent carbon atoms;

(d) when W is S, then R is H, A is A-1, and Y is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃ or CH(OCH₃)₂ ;

(e) the total number of carbon atoms of R₁₂ and R₁₃ must be less than or equal to four; and

(f) when the total number of carbon atoms of X and Y is greater than four, then the number of carbons of R₁ must be less than or equal to two and the number of carbons of Q must be less than or equal to six.

In the above definitions, the term "alkyl," used either alone or in compound words such as "alkylthio" or "haloalkyl," denotes straight chain or branched alkyl, e.g. methyl, ethyl, n-propyl, isopropyl or the different butyl isomers.

Alkoxy denotes methoxy, ethoxy, n-propoxy, isopropoxy and the different butoxy isomers.

Alkenyl denotes straight chain or branched alkenes, e.g. vinyl, 1-propenyl, 2-propenyl, 3-propenyl and the different butenyl isomers.

Alkynyl denotes straight chain or branched alkynes, e.g. ethynyl, 1-propynyl, 2-propynyl and the different butynyl isomers.

Cycloalkyl denotes cyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl.

The term "halogen," either alone or in compound words such as "haloalkyl," denotes fluorine, chlorine, bromine and iodine.

In terms such as C₂ -C₃ alkylthioalkyl, the specified number of carbon atoms is meant to define the total number of carbon atoms in that substituent group. For example, C₂ -C₃ alkylthioalkyl would designate CH₂ SCH₃, CH₂ SC₂ H₅, CH₂ CH₂ SCH₃ or CH(CH₃)SCH₃, and C₂ -C₅ alkoxyalkoxy would represent OCH₂ OCH₃ through O(CH₂)₄ OCH₃ or OCH₂ O(CH₂)₃ CH₃ and the various structural isomers embraced therein.

Alkoxycarbonyl denotes methoxycarbonyl, ethoxycarbonyl, propoxycarbonyl and isopropoxycarbonyl.

Alkylcarbonyl denotes e.g. acetyl, propionyl, and the different butyryl isomers.

Alkylsulfonyl denotes methylsulfonyl, ethylsulfonyl and the different propylsulfonyl and butylsulfonyl isomers.

Alkylthio, alkylsulfinyl, alkylamino, alkylsulfamoyl etc. are defined in an analogous manner.

The compounds of the invention which are preferred for reasons of increased ease of synthesis and/or greater herbicidal efficacy are:

(1) Compounds of Formula I where Q is ##STR12## wherein R₃ is C₁ -C₃ alkyl;

R₇ is H, F, Cl, Br, CN, CH₃ or OCH₃ ;

R₈ is H, F, Cl, Br, I, CN, OH, C₁ -C₃ alkyl, C₁ -C₃ alkoxy, C₂ -C₃ alkoxycarbonyl, di(C₁ -C₃ alkyl)aminosulfamoyl, C₁ -C₃ alkylthio or C₁ -C₃ alkylsulfonyl;

R₉ and R₁₀ are independently H, CH₃, F, Cl or may be taken together to form C═O; and

R₁₁ is H or C₁ -C₃ alkyl;

provided that

(a) when R₇ and R₈ are attached to the same carbon atom as in Q-1, Q-2 or Q-3, or in Q-4 through Q-10, and R₇ is OCH₃, then R₈ is other than F, Cl, Br, I or OH; and

(b) when R₇ and R₈ are attached to the same carbon atom as in Q-1, Q-2 or Q-3, or in Q-4 through Q-10, and R₈ is F, Cl, Br, I or OH, then R₇ is other than OCH₃.

(2) Compounds of Preferred 1 where

A is A-1,

W is O; and

R is H.

(3) Compounds of Preferred 2 where

R₁ is selected from H, F, Cl, NO₂, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, C₁ -C₂ alkoxy, C₁ -C₂ alkylthio, CH₂ OCH₃ or CH₂ SCH₃ ;

R₁₃ is H or CH₃ ;

R₁₄ is H, C₁ -C₂ alkyl, CH₂ CH═CH₂ or CH₂ C.tbd.CH;

X is CH₃, OCH₃, OC₂ H₅, Cl, F, Br, OCF₂ H, CH₂ F, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CF₃, CH₂ Cl or CH₂ Br; and

Y is H, C₁ -C₃ alkyl, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OC₂ H₅, OCH₂ CH₂ OCH₃, CH₂ SCH₃, OCF₂ H, SCF₂ H, cyclopropyl, C.tbd.CH or C.tbd.CCH₃.

(4) Compounds of Preferred 3 where

L is L-1; and

Q is Q-1, Q-2 or Q-4.

(5) Compounds of Preferred 4 where Q is Q-1;

(6) Compounds of Preferred 5 where

R₁ is H, Cl, CH₃, OCH₃ or SCH₃ and is not in the 4-position;

R₇ is H, F, Cl, CH₃ or OCH₃ ;

R₈ is H, F, Cl, CH₃ or OCH₃ ; and

R₉ and R₁₀ are independently H, CH₃, F or Cl.

(7) Compounds of Preferred 3 where

L is L-2 or L-3; and

Q is Q-1, Q-2 or Q-4.

(8) Compounds of Preferred 7 where

R₁ is H;

R₇ is H, F, Cl, CH₃ or OCH₃ ;

R₈ is H, F, Cl, CH₃ or OCH₃ ;

R₉ and R₁₀ are independently H, CH₃, F or Cl; and

R₁₁ is H or CH₃.

(9) Compounds of Preferred 3 where

L is L-4 or L-5; and

Q is Q-1, Q-2 or Q-4.

(10) Compounds of Preffered 9 where

R₁ is H;

R₇ is H, F, Cl, CH₃ or OCH₃ ;

R₈ is H, F, Cl, CH₃ or OCH₃ ;

R₉ and R₁₀ are independently H, CH₃, F, or Cl; and

R₁₁ is H or CH₃.

(11) Compounds of Preferred 3 where

L is L-6; and

Q is Q-1, Q-2 or Q-4.

(12) Compounds of Preferred 11 where

R₁ is H;

R₇ is H, F, Cl, CH₃ or OCH₃ ;

R₈ is H, F, Cl, CH₃ or OCH₃ ;

R₉ and R₁₀ are independently H, CH₃, F or Cl; and

R₁₁ is H or CH₃.

The compounds of the invention which are specifically preferred for reasons of their expected greatest ease of synthesis and/or greatest herbicidal efficacy are:

2-(2,2-dichlorocyclopropyl)-N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]benzenesulfonamide, m.p. 193°-195° C.;

2-(2,2-dichlorocyclopropyl)-N-[(4-methoxy-6-methyltriazin-2-yl)-aminocarbonyl]benzenesulfonamide, m.p. 168°-170° C.; and

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranylmethyl)benzenesulfonamide, m.p. 157°-159° C.(d).

DETAILED DESCRIPTION OF THE INVENTION Synthesis

The compounds of Formula I can be prepared by reacting an appropriate sulfonyl isocyanate or sulfonyl isothiocyanate, II, with an appropriately substituted aminoheterocycle, III, as shown in Equation 1, where R, W, A and L are as previously defined. ##STR13##

The reaction is best performed in an inert solvent such as methylene chloride or toluene at 25° to 100° C., for 1 to 24 hours. Isolation of the product can be achieved by concentrating the solution and trituration with an appropriate solvent such as butyl chloride.

Alternatively, compounds of Formula I, where W is O, can be prepared by reacting the sulfonamides of Formula IV with the carbamates of Formula V (R'=CH₃) in the presence of an excess of trimethylaluminum, as shown in Equation 2, where L, R and A are as previously defined, provided R₁ is other than CO₂ R^(III). ##STR14##

The reactions are best performed in an inert solvent such as methylene chloride at the reflux point of the solution (40° C.) for 10 to 24 hours. Isolation of the product is best achieved by exposing the reaction mixture to acetic acid, separation of the layers and concentrating the organic layer to a solid.

Alternatively, compounds of Formula I can be prepared by exposing a phenyl carbamate V (R'=Ph) to the sulfonamide IV in an appropriate solvent such as dioxane at 25° to 100° C. in the presence of a strong base such as 1,8-diazabicyclo[5.4.0]undec-7-ene; acid workup affords the desired product, as disclosed in European Patent Application (EP-A) No. 44,807. Compounds of Formula I can also be prepared from a phenyl carbamate V and the tert-butyldimethylsilyl-protected sulfonamide IV (LSO₂ NHSi(CH₃)₂ -t-Bu). Addition of tetrabutylammonium fluoride to a mixture of the carbamate and sulfonamide affords after workup the desired product. The required carbamates can be prepared from the corresponding amines, III, and dimethyl or diphenylcarbonate or methyl or phenylchloroformate and a base such as sodium hydride.

The sulfonyl isocyanates, II, used in the preparation of I are known in the art and can be prepared by known methods. For example, isocyanates can be prepared by exposing an appropriate benzene or heterocyclic sulfonamide to phosgene in the presence of an alkyl isocyanate and an amine catalyst such as 1,4-diazabicyclo[2.2.2]octane at the reflux point of the solvent; see H. Ulrich and A. A. Y. Sayigh, Newer Methods of Preparative Organic Chemistry, Vol. VI, p. 223-241. Academic Press, New York and London, W. Forest Ed.

The sulfonyl isothiocyanates, II, used in the preparation of I, where W is S, can be prepared according to the procedure of K. Hartke, Arch. Pharm., 299, 174 (1966).

Sulfonamides of Formula L-1 (compound 3) where Q is Q-1, n=0, R₁, and R₇ through R₁₀ are as previously defined can be prepared in one or more of the ways outlined in Equations 3 through 7. ##STR15##

The addition of carbenes to styrene is well known in the art. For further details of such transformations see Keller, W. E., "Compendium of Phase-Transfer Reactions and Related Synthetic Methods", Fluka A.G., Switzerland, p 39-64, 1979. ##STR16##

An alternate sequence, outlined below in Equation 5, can be employed in selected cases where lithiation of 2 may be a problem due to functional group incompatibility with n-BuLi, (i.e., R₇ =CO₂ CH₃). ##STR17##

The sulfonamide 3 can also be prepared by direct alkylation with the preformed cyclopropyl methyl halide 8 as outlined in Equation 6. ##STR18##

For further details pertaining to this modification of the Ullmann reaction see, S. Gronowitz, and S. Lilgefors, Chemica Scripta, 13, 157-161 (1978-79) and A. Minato, K. Tamo, T. Hayasi, K. Suzuki and M. Kumada; Tetrahedron Letters, 22, 5319 (1981).

In Equation 5 the dihaloethane 9 may be replaced with other electrophiles such as propylene oxide and its derivatives, as shown in Equation 7. ##STR19##

The ortho-lithiation of compounds such as 1, 2, 5 and 5a is well known to those skilled in the art. For further details pertaining to this type of transformation see Meyers, A. I., Michlich, B. D., and Nolan, R. L., J. Org Chem., 39, 2783, 1974.

Sulfonamides of Formula L-1 (Compound 12) where n is 1, Q is Q-1 through Q-3 and R₁, R₃ and R₇ through R₁₃ are as previously defined can be prepared in a similar manner to that already described in Equations 3, 4 and 6, with slight modifications of the starting material. For example cyclopropanation of the styrene homolog 13, followed by ortho-lithiation chemistry would afford the target Compound 12 as outlined in Equation 8. ##STR20##

In an analogous manner to Equation 6, cyclopropane 12 can be prepared as outlined in Equation 9. ##STR21##

Alternatively, sulfonamide 12 can be prepared by a modified Ullmann reaction utilizing sulfonamide 5 as the starting material as outlined in Equation 10. ##STR22##

The epoxy sulfonamides of Formula L-1 (Compound 15) where Q is Q-2 and n, R₁, R₇, R₈ and R₁₁ are as previously defined can be prepared directly from olefins 1, 4 and 13 via epoxidation using m-chloroperbenzoic acid as described in Equation 11. ##STR23##

Further details pertaining to olefin epoxidations may be found i Org. Syn., Coll. Vol. 1, 494 (1944).

The aziridine sulfonamides where Q is Q-3 and n, R₁, R₃, R₇, R₈ and R₁₁ are as previously defined such as compound 16 can also be prepared from the corresponding olefins using the procedure outlined in Equation 12. ##STR24##

For further details see Gebelein, C. O., Swift, G., Swern, D., J. Org. Chem., 32, 3314 (1967).

Sulfonamides of Formula L-2, L-3, L-4, L-5 and L-6, where Q is Q-1 through Q-3 and n, R₁, R₂, R₃ and R₇ through R₁₁ are as previously defined can be prepared using one or more of the routes previously outlined in Equations 3 through 12.

For example, in the case of L-3, sulfonamide 18 can be prepared using the same route described in Equation 3 or 4. This is outlined in Equation 13. ##STR25##

Sulfonamides (such as 20) containing a four-membered ring where R₁, R₇ and R₈ are as previously defined may be prepared in one or more of the ways outlined in Equations 14 through 17b. ##STR26##

For a discussion of photochemical 2+2 cycloadditions of styrene with olefins, aldehydes and ketones (the Paterno-Buchi reaction) see Silversmith, Kitahara, Caserio and Roberts, J. Am. Chem. Soc., 80, 5840 (1958).

An alternate synthesis of compounds such as 20 is via the anionic ring closure of chloride 25 as outlined in Equation 16. ##STR27##

In the similar manner the oxetane ring systems can be formed as shown in Equation 17a and 17b. ##STR28##

The methodology described in Equations 15, 17a and 17b can also be used to prepare the thio and amine analogs, that is sulfonamides of Formula L-1 where Q is Q-7 through Q-10 and R₁, R₃, R₇ and R₈ are as previously defined, and n=0 (i.e., 29 and 30). ##STR29##

Examples of anionic four membered ring closures may be found in Corey, E. J. and Seebach, D., Org. Synth., 50, 72 (1970).

Sulfonamides of Formula L-2, L-3, L-4, L-5 and L-6 where Q is Q-4 through Q-10 and R, R₁, R₂, R₃, R₇ and R₈ are as previously defined can be prepared in a similar manner to that already taught for L-1 in Equations 14 through 17b utilizing the appropriate starting sulfonamides (e.g. 19) as described previously.

In the case where n is 1 the corresponding sulfonamides such as 31 and 32 can be prepared by the procedures outlined in Equation 18a and 18b. ##STR30##

Sulfonamide 34 where R₁₂ is OH, R₁₃ is H (n=1) can be prepared as outlined in Equation 19. ##STR31##

The use of the tert-butyldimethylsilyl group allows for low temperature generation of the anion and mild removal of the protecting group. In the same manner alkylation of 36 with ketones such as cyclobutanone allows for the preparation of sulfonamide 37 as outlined in Equation 20. ##STR32##

Preparation of a heterocyclic sulfonamide wherein R₁₂ is H and R₁₃ is OH (n=1) is accomplished in the same way as already taught for an aromatic system in Equations 19 and 20. For example, sulfonamide 38 can be prepared from protected pyrazole sulfonamide 39 as outlined in Equation 21. ##STR33##

Sulfonamides such as 34 or 38 can be used to prepare sulfonamides such as 40. Generation of the alkoxide with sodium hydride followed by the addition of the appropriate alkylating group affords protected alcohols such as 40. ##STR34##

An alternate preparation of protected alcohols, for example 41, is to trap directly the incipient lithium alkoxide (42) resulting from the condensation of the anion of 36 with aldehydes and ketones. This is depicted in Equation 23. ##STR35##

For further information pertaining to the synthesis of pyrazole sulfonamides see: EP-A-95,925; for thiophene sulfonamides, EP-A-30,142; for pyridine sulfonamides, EP-A-13,480, and benzyl sulfonamides, EP-A-51,466 and U.S. Pat. No. 4,420,325.

The heterocyclic amines of Formula III can be prepared by methods known in the literature or simple modifications thereof, by those skilled in the art. For instance, EP-A-84,224 (published July 27, 1983) and W. Braker et al, J. Am. Chem. Soc. 1947, 69, 3072 describe methods for preparing aminopyrimidines and triazines substituted by acetal groups. Also, South African Patent Application Nos. 825,045 and 825,671 describe methods for preparing aminopyrimidines and triazines substituted by haloalkyl or haloalkylthio groups such as OCH₂ CH₂ F, OCH₂ CF₃, SCF₂ H, and OCF₂ H among other groups. South African Patent Application No. 837,434 (published Oct. 5, 1983) describes methods for the synthesis of cyclopropylpyrimidines and triazines substituted by such groups as alkyl, haloalkyl, alkoxy, haloalkoxy, alkylamino, dialkylamino, and alkoxyalkyl.

The 5,6-dihydrofuro[2.3-d]pyrimidin-2-amines, and the cyclopenta[d]pyrimidin-2-amines, of Formula III, where A is A-2, and the 6,7-dihydro-5H-pyrano[2.3-d]pyrimidin-2-amines, the Formula III, where A is A-3, can be prepared as described in EP-A No. 15,863. The furo[2.3-d]pyrimidin-2-amines, of Formula III, where A is A-4, are described in EP-A No. 46,677. Heterocycles of Formula III, where A is A-5, can be prepared as described in EP-A No. 73,562. Heterocycles of Formula III, where A is A-6, can be prepared by methods taught in EP-A-94,260. Heterocycles of Formula III, where A is A-7, can be prepared by methods taught in EP-A-125,864.

In addition, general methods for preparing aminopyrimidines and triazines have been reviewed in the following publications.

"The Chemistry of Heterocyclic Compounds", a series published by Interscience Publishers, Inc., New York and London;

"Pyrimidines", Vol. 16 of the same series by D. J. Brown;

"s-Triazines and Derivatives", Vol. 13 of the same series by E. M. Smolin and L. Rapaport; and

F. C. Schaefer, U.S. Pat. No. 3,154,547 and K. R. Huffman and F. C. Schaefer, J. Org. Chem., 28, 1812 (1963), which describe the synthesis of triazines.

Agriculturally suitable salts of compounds of Formula I are also useful herbicides and can be prepared in a number of ways known to the art. For example, metal salts can be made by contacting compounds of Formula I with a solution of an alkali or alkaline earth metal salt having a sufficiently basic anion (e.g., hydroxide, alkoxide or carbonate). Quaternary amine salts can be made by similar techniques.

Salts of compounds of Formula I can also be prepared by exchange of one cation for another. Cationic exchange can be effected by direct contacting of an aqueous solution of a salt of a compound of Formula I (e.g., alkali metal or quaternary amine salt) with a solution containing the cation to be exchanged. This method is most effective when the desired salt containing the exchanged cation is insoluble in water, e.g., a copper salt, and can be separated by filtration.

Exchange may also be effected by passing an aqueous solution of a salt of a compount of Formula I (e.g., an alkali metal or quaternary amine salt) through a column packed with a cation exchange resin containing the cation to be exchanged. In this method, the cation of the resin is exchanged for that of the original salt and the desired product is eluted from the column. This method is paticularly useful when the desired salt is water-soluble, e.g., a potassium, sodium or calcium salt.

Acid addition salts, useful in this invention, can be obtained by reacting a compound of Formula I with a suitable acid, e.g., p-toluenesulfonic acid, trichloroacetic acid or the like.

The preparation of the compounds of this invention is illustrated by the following examples.

EXAMPLE 1 Preparation of 2-Ethenylbenzenesulfonamide

2-Bromostyrene (10.0 g, 54.9 mmol) was added dropwise to n-BuLi in 250 ml of tetrahydrofuran at -78° C. After stirring for 15 minutes the solution was added via a cannula to a solution of sulfurylchloride fluoride (9.7 g, 82.4 mmol) in 50 ml of tetrahydrofuran cooled to -78° C. The reaction mixture was quenched with brine and separated. The organic layer was dried and concentrated to approximately half-volume. This solution was added to anhydrous ammonia (100 ml) cooled to -78° C. The reaction was warmed to room temperature, excess ammonia was removed and the solids were filtered off. The filtrate was concentrated and the resulting oil was triturated with butyl chloride and ethyl acetate to yield the desired sulfonamide, m.p. 103°-105° C.

EXAMPLE 2 Preparation of 2-(2-Oxiranyl)benzenesulfonamide

A solution consisting of 2-ethenylbenzenesulfonamide (1.5 g, 8.1 mmol) m-chloroperbenzoic acid (1.4 g, 8.1 mmol) and potassium carbonate (1.1 g, 8.1 mmol) in 150 ml of chloroform was stirred for 4 days at room temperature. The reaction was filtered and the filtrate was washed with saturated sodium bicarbonate. The organic layer was separated, dried and concentrated. The resulting oil was flash chromatographed (methylene chloride) to yield the subject compound as a white solid, m.p. 136°-139° C.

EXAMPLE 3 Preparation of 1-Bromo-2-(2,2-Dichlorocyclopropyl)-benzene

A 20 ml solution of 50% sodium hyroxide was added dropwise to 2-bromostyrene (10.0 g, 54.9 mmol) in 100 ml of chloroform. The reaction mixture was warmed to 45° C. for 1 hour. After cooling the solution was separated and the organic layer was dried over magnesium sulfate and concentrated. The resulting liquid was flash chromatographed, affording 11.6 g of the desired compound.

EXAMPLE 4 Preparation of N-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranyl)benzenesulfonamide

To a stirring solution of the 2-(2-oxiramyl)benzenesulfonamide (75 mg, 0.376 mmol) and 4,6-dimethoxy-2-aminophenoxycarbonyl pyrimidine (103 mg, 0.37 mmol) in 5 ml of acetonitrile was added 1,8-diazabicyclo[5.4.0]undec-7-ene (57 mg, 0.37 mmol). The reaction was stirred for 3 hours followed by quenching with 3 ml of 5% hydrochloric acid. The solution was diluted with ethyl acetate, separated and dried. The organics were concentrated to yield 140 mg of the desired product, m.p. 177°-179° C.; NMR (200 MHz, CDCl₃)δ: 2.3 (dd, 1H); 3.1 (dd, 1H); 3.95 (s, 6H); 4.7 (dd, 1H); 5.88 (s, 1H); 7.0 (br s, 1H); 7.55 (m, 3H) and 8.2 (dd, 1H).

EXAMPLE 5 Preparation of 2-(2,2-Dichlorocyclopropyl)-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]benzenesulfonamide

To a stirring solution of 2-(2,2-dichlorocyclopropyl)benzenesulfonamide (200 mg, 0.75 mmol) and 4-methyl-6-methoxy-2-aminophenoxycarbonyl pyrimidine (195 mg, 0.75 mmol) was added 1,8-diazabicyclo[5.4.0]undec-7-ene (115 mg, 0.75 mmol). Work-up as described in example 4 afforded 180 mg of the desired compound, m.p. 187°-191° C.; NMR (200 MHz, CDCl₃)δ: 2.05 (dd, 2H); 2.41 (s, 3H); 3.79 (dd, 1H); 3.94 (s, 3H); 6.27 (s, 1H); 7.2 (d, 1H); 7.57 (m, 3H) and 8.4 (dd, 1H).

EXAMPLE 6 2-[(Cyclopropyl)(hydroxy)methyl]-N-[(dimethyl((1,1-dimethylethyl)silyl]benzenesulfonamide

To a stirring solution of n-BuLi (5.2 g, 80.8 mmol) in 300 ml of THF cooled to -10° C. was added dropwise tert-butyldimethylsilylbenzenesulfonamide (10.0 g, 36.7 mmol) in 25 ml of THF. The solution was stirred for one hour. After cooling to -78° C., cyclopropyl aldehyde (2.8 g, 40.0 mmol) was added. The reaction mixture was stirred for 30 minutes, then quenched with brine. The organic layer was separated, dried over magnesium sulfate and concentrated in vacuo. Flash chromatography (20% EtOAc:hexane, v/v) afforded 2.7 g of the desired product as a viscous oil; NMR (200 MHz, CDCl₃): δ 0.24 (d, 6H), 0.4 (m, 1H), 0.45-0.8 (m, 3H), 0.88 (s, 9H)), 1.6 (m, 1H), 2.85 (d, 1H), 4.9 (dd, 1H), 5.30 (s, 1H), 5.67 (brs, 1H), 7.41 (t, 1H), 7.54 (t, 1H), 7.76 (d, 1H), 7.98 (d, 1H).

EXAMPLE 7 N-[(4,6-Dimethylpyrimidin-2-yl)aminocarbonyl]-2-(1-hydroxycyclobutyl)benzenesulfonamide

To a mixture of the phenylcarbamate of 4,6-dimethyl-2-aminopyrimidine (178 mg, 0.73 mmol) and tert-butyldimethylsilane-protected 2-(1-hydroxycylcobutane)benzenesulfonamide in 5 ml of acetonitrile was added tetrabutylammonium fluoride (231 mg, 0.73 mmol). The reaction mixture was stirred for 5 minutes followed by the addition of 5% HCl. The resulting solids were collected and dried to give 250 mg of the desired product; m.p. 148°-150° C.; NMR (200 MHz, CDCl₃); δ 2.45 (s, 7H), 2.58 (m, 5H), 6.76 (s, 1H), 7.47-7.75 (m, 4H), 8.32 (d, 1H).

                  TABLE OF STRUCTURES                                              ______________________________________                                         General Structure I                                                             ##STR36##                                                                     where W is O unless otherwise indicated by *, where W is S.                    For ring systems Q-4 through Q-10, the substituents                            R.sub.7 and R.sub.8 are attached as follows                                     ##STR37##                                                                     General Structure II                                                            ##STR38##                                                                      ##STR39##                                                                     For ring systems Q-4 through Q-10, the substituents                            R.sub.7 and R.sub.8 are attached as follows                                     ##STR40##                                                                     General Structure IIa                                                           ##STR41##                                                                      ##STR42##                                                                     General Structure IIb                                                           ##STR43##                                                                      ##STR44##                                                                     General Structure III                                                           ##STR45##                                                                     General Structure IV                                                            ##STR46##                                                                     L-2 and L-3 are as in General Structure II. n = 0                              General Structure V                                                             ##STR47##                                                                     L-2 and L-3 are as in General Structure II,                                    R.sub.9 and R.sub.10 are C = O n = 0                                      

                                      TABLE I                                      __________________________________________________________________________     General Structure I (wherein R.sub.12 and R.sub.13 are H)                      Q  n R  R.sub.1                                                                          R.sub.7                                                                              R.sub.8                                                                               R.sub.9                                                                           R.sub.10                                                                          R.sub.11                                                                          X      Y     Z  m.p.(°C.)               __________________________________________________________________________     Q-1                                                                               0 H  H H     H      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH 197- 198.5                     Q-1                                                                               0 H  H H     H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH 209-210                        Q-1                                                                               0 H  H H     H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH 202-204                        Q-1                                                                               0 CH.sub.3                                                                          H H     H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N  144-146                        Q-1                                                                               0 H  H H     H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N  190-191                        Q-1                                                                               0 H  H H     H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N  174-176                        Q-1                                                                               0 H  H H     H      H  H  -- Cl     OCH.sub.3                                                                            CH 192-194                        Q-1                                                                               0 H  H H     F      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     F      H  H  -- CH.sub.3                                                                              CH.sub. 3                                                                            N                                 Q-1                                                                               0 H  H H     F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH 174-177                        Q-1                                                                               0 H  H H     Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N  172-175                        Q-1                                                                               0 H  H Cl    H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH 186-188                        Q-1                                                                               0 H  H Cl    H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N  156-160                        Q-1                                                                               0 H  H H     Br     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Br    H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     I      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H H     H      H  H  -- NHCH.sub.3                                                                            OCH.sub.2 CH.sub.3                                                                   N  203-206                        Q-1                                                                               0 H  H H     CN     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CN    H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub. 3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH 155-159                        Q-1                                                                               0 H  H H     CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH 180-182                        Q-1                                                                               0 H  H H     CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH 215-216                        Q-1                                                                               0 H  H CH.sub.3                                                                             H      H  H  -- Cl     OCH.sub.3                                                                            N  175-176                        Q-1                                                                               0 H  H CH.sub.3                                                                             H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N  154-157                        Q-1                                                                               0 H  H H     CH.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.2 CH.sub.3                                                                    H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH 182-185                        Q-1                                                                               0 H  H H     Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N  139-142                        Q-1                                                                               0 H  H H     Cl     H  H  -- Cl     OCH.sub.3                                                                            CH 185-187                        Q-1                                                                               0 H  H H     Cl     H  H  -- OCH.sub.2 CH.sub.3                                                                    NHCH.sub.3                                                                           CH 154-158                        Q-1                                                                               0 H  H H     Br        CH.sub.3                                                                          -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     Br     H  Cl -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     Br     H  F  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H H     Br     H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     Br     H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     Br     H  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     I      H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CN     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CN     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CN     H  Cl -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     CN     H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CN     H  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CN     CH.sub.3                                                                          H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H H     OCH.sub.3                                                                             H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     OCH.sub.3                                                                             H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     OCH.sub.3                                                                             H  Cl -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     OCH.sub.3                                                                             Cl H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     OCH.sub.3                                                                             F  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     OCH.sub.3                                                                             H  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SCH.sub.3                                                                             H  CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SCH.sub.3                                                                             H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SCH.sub.3                                                                             H  Cl -- CH.sub.3                                                                              OCH.sub. 3                                                                           CH                                Q-1                                                                               0 H  H H     OCH.sub.3                                                                             H  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     OCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CH.sub.3 O                                                                           H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     OCH.sub.2 CH.sub.3                                                                    H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CO.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     SCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CH.sub.3                                                                              H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CH.sub.3                                                                              CH.sub.3                                                                          H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CH.sub.3                                                                              H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CH.sub.3                                                                              Br H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     F      H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     F      H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     Cl     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     Cl     H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     Cl     H  Cl -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     Cl     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     Cl     H  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     SO.sub.2 CH.sub.3                                                                     H  Br -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H F     F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H F     F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H F     F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H F     F      H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Cl     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH 187-191                        Q-1                                                                               0 H  H Cl    Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH 193-195                        Q-1                                                                               0 H  H Cl    Cl     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N  168-170                        Q-1                                                                               0 H  H Cl    Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N  190-193                        Q-1                                                                               0 H  H Cl    Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH 233-235                        Q-1                                                                               0 H  H Cl    Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N  195-199                        Q-1                                                                               0 H  H Cl    Cl     H  H  -- Cl     OCH.sub.3                                                                            CH 199-202                        Q-1                                                                               0 H  H Br    Br     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    Br     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    Br     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    Br     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    Br     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Br    Br     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H I     I      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CN    CN     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CN    CN     H  H  -- OCH.sub.3                                                                             CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  H  -- Cl     OCH.sub.3                                                                            CH 154-156                        Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N  152-155                        Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH 179-180                        Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H F     F      H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H F     F      H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      H  Cl -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H F     F      H  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    Cl     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    Cl     H  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Cl     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Cl     H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    Cl     H  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    Br     H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Br    Br     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    Br     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    Br     H  Cl -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H Br    Br     Cl H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    Br     H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    Br     H  Br -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              CH.sub.3                                                                          H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CO.sub.2 CH.sub.3                                                                    CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      CH.sub.3                                                                          CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      F  F  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H F     F      F  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H F     F      F  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H F     F      Cl Cl -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      Cl Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      Br Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     F      Br Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    Cl     CH.sub.3                                                                          CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    Cl     CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Cl    Cl     CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Cl     F  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Cl     F  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    Cl     Cl Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    Cl     Cl Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Cl     Br Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Cl     Br Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H I     I      CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CN    CN     CH.sub.3                                                                          CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     CH.sub.3                                                                          CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     F  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CN    CN     F  F  -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CN    CN     F  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CN     Cl Cl -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H CN    CN     Br Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CN    CN     Br Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              F  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              Cl Cl -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              Cl Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              Cl Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              Br Br -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CH.sub.3                                                                              Br Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             CH.sub.3                                                                          CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             Cl Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             F  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             F  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             F  F  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             Br Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             Br Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     Cl     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     Br     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     CN     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H F     CH.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H F     OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H F     CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     SCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H F     SO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    F      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Cl    F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Br     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    CN     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    CH.sub.3                                                                              H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Cl    OCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Cl    CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H Cl    SCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    SO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Br    Cl     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    Br     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    CN     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H Br    CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    CH.sub.3                                                                              H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    CH.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    OCH.sub. 3                                                                            H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H Br    CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Br    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    SCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H I     F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H I     Cl     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H I     Br     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H I     CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CN    Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CN    Br     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CN    CH.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CN    CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H CN    SCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H H     F      F  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     F      F  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     F      Cl Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     F      Br F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              F  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CH.sub.3                                                                              F  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CH.sub.3                                                                              F  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              Br CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              Cl CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     Cl     F  Cl -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               0 H  H H     Cl     F  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     Cl     Br Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     Cl     F  CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CN     F  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CN     F  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CN     F  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CN     Cl CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CN     Cl Br -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              F  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              F  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              F  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CH.sub.3                                                                              Cl Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     CH.sub.3                                                                              Cl Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.3                                                                              Br CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.2 CH.sub.3                                                                     F  Cl.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     CH.sub.2 CH.sub.2 CH.sub.3                                                            F  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     OCH.sub.3                                                                             F  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     OCH.sub.3                                                                             F  Br -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H H     OCH.sub.3                                                                             F  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H H     OCH.sub.3                                                                             Cl Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     Cl     F  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H F     Cl     F  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H F     Br     Cl CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Cl    CH.sub.3                                                                              CH.sub.3                                                                          F  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               0 H  H Br    OCH.sub.3                                                                             CH.sub.3                                                                          F  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H SCH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                     F  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Br    Cl     F  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H Br    I      F  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               0 H  H CH.sub.3                                                                             CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                          Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Br     Cl Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H Cl    Br     Cl CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H I     F      F  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    F      F  Cl -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               0 H  H CN    Br     Cl CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     H      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H H     H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     H      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H H     H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     H      H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     F      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H H     F      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H H     F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               H H  H Cl    H      H  -- OCH.sub.3                                                                         OCH.sub.3                                                                             CH                                      Q-1                                                                               1 H  H H     Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H Cl    H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     Br     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H Br    H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     I      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H I     H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CN     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CN    H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             H      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             H      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CH.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CH.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     CH.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H H     OCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H CH.sub.3 O                                                                           H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     OCH.sub.2 CH.sub.3                                                                    H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H H     CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     CO.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H H     SCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     SCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H SO.sub.2 CH.sub.3                                                                    H      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CH.sub.3                                                                              CH.sub.3                                                                          H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CH.sub.3                                                                              H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     CH.sub.3                                                                              Br H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     F      H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     F      H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     Cl     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     Cl     H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     Cl     H  Cl -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     Cl     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     Cl     H  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H H     SO.sub.2 CH.sub.3                                                                     H  Br -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H F     F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H F     F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H F     F      H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H F     F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H F     F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H F     F      H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    Cl     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    Cl     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Cl    Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Cl    Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H Cl    Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H Cl    Cl     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    Br     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    Br     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    Br     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    Br     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    Br     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H I     I      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    CN     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    CN     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CN    CN     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H F     F      H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H F     F      H  CH.sub.3                                                                          -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H F     F      H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H F     F      H  Cl -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H F     F      H  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Cl    Cl     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Cl    Cl     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    Cl     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    Cl     H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Cl    Cl     H  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    Br     H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H Br    Br     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    Br     H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    Br     H  Cl -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H Br    Br     Cl H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    Br     H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    Br     H  Br -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    CN     H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    CN     H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    CN     H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              CH.sub.3                                                                          H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              H  Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             H  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CN    CN     CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H CN    CN     F  F  -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H CN    CN     F  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    CN     Cl Cl -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H CN    CN     Br Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CN    CN     Br Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              F  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              Cl Cl -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              Cl Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              Cl Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              Br Br -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.3                                                                              Br Br -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             CH.sub.3                                                                          CH.sub.3                                                                          -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             CH.sub.3                                                                          CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             Cl Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             F  F  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             F  F  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             F  F  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H OCH.sub.3                                                                            OCH.sub.3                                                                             Br Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H Cl    OCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H Cl    CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H Cl    SCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Cl    SO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    Cl     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H Br    Cl     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    Br     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    CN     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             N                                 Q-1                                                                               1 H  H Br    CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    CH.sub.3                                                                              H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    CH.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    OCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    OCH.sub.2 CH.sub.3                                                                    H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H Br    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    SCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H I     F      H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H I     Cl     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H I     Br     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H I     CH.sub.3                                                                              H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    F      H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CN    Cl     H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    Br     H  H  -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CN    CH.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H F     Cl     F  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H F     Cl     F  CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H F     Br     Cl CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Cl    CH.sub.3                                                                              CH.sub.3                                                                          F  -- CH.sub.3                                                                              CH.sub.3                                                                             CH                                Q-1                                                                               1 H  H Br    OCH.sub.3                                                                             CH.sub.3                                                                          F  -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Br    Cl     F  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H Br    I      F  Cl -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                     CH.sub.3                                                                          Br -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    Br     Cl Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H Cl    Br     Cl CH.sub.3                                                                          -- CH.sub.3                                                                              OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CO.sub.2 CH.sub.3                                                                    SCH.sub.3                                                                             F  Cl -- CH.sub.3                                                                              OCH.sub.3                                                                            N                                 Q-1                                                                               1 H  H I     F      F  Br -- OCH.sub.3                                                                             OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    F      F  Cl -- Cl     OCH.sub.3                                                                            CH                                Q-1                                                                               1 H  H CN    Br     Cl CH.sub.3                                                                          -- OCH.sub.3                                                                             OCH.sub.3                                                                            N                                 __________________________________________________________________________     Q   n R   R.sub.1                                                                             R.sub.7                                                                               R.sub.8                                                                               R.sub.11                                                                             X   Y    Z  m.p.(°C.)                __________________________________________________________________________     Q-2 0 H   H    H      H      H     CH.sub.3                                                                           CH.sub.3                                                                            CH 158-160                         Q-2 0 H   H    H      H      H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH 177-179                         Q-2 0 H   H    H      H      H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 H   H    H      H      H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      H      H     Cl  OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      CH.sub.3                                                                              H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      CH.sub.3                                                                              H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      CH.sub.3                                                                              H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      CH.sub.3                                                                              H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      Cl     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      Cl     H     OCH.sub.3                                                                          CH.sub.3                                                                            N                                  Q-2 0 H   H    H      Cl     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      Cl     H     Cl  OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      F      H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 H   H    H      F      H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2 0 H   H    H      F      H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2 0 H   H    H      F      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      F      H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      F      H     Cl  OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      CN     H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      CN     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      OCH.sub.3                                                                             H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      OCH.sub.3                                                                             H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      OCH.sub.3                                                                             H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 H   H    H      CO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2 0 H   H    H      CO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2 0 H   H    H      CO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      CO.sub.2 CH.sub.3                                                                     H     Cl  OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      SO.sub.2 N(CH.sub.3).sub.2                                                            H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 H   H    H      SO.sub.2 N(CH.sub.3).sub.2                                                            H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      SO.sub.2 N(CH.sub.3).sub.2                                                            H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      SO.sub.2 N(CH.sub.3).sub.2                                                            H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      SCH.sub.3                                                                             H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      SCH.sub.3                                                                             H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2 0 H   H    H      SCH.sub.3                                                                             H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2 0 H   H    H      SCH.sub.3                                                                             H     Cl  OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      SO.sub.2 CH.sub.3                                                                     H     CH.sub. 3                                                                          CH.sub.3                                                                            CH                                 Q-2 0 H   H    H      SO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      SO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 0 H   H    F      F      H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2 0 H   H    F      F      H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2 0 H   H    Cl     Cl     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    Cl     Cl     H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 H   H    F      Cl     H     OCH.sub.3                                                                          CH.sub.3                                                                            N                                  Q-2 0 H   H    F      CH.sub.3                                                                              H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2 0 H   H    CH.sub.3                                                                              CH.sub.3                                                                              H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    CH.sub.3                                                                              CH.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    F      Br     H     Cl  OCH.sub.3                                                                           CH                                 Q-2 0 H   H    Br     Br     H     Cl  OCH.sub.3                                                                           CH                                 Q-2 0 H   H    Br     Br     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    CO.sub.2 CH.sub.3                                                                     CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 H   H    CO.sub.2 CH.sub.3                                                                     CO.sub.2 CH.sub. 3                                                                    H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    CO.sub.2 CH.sub.3                                                                     CO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    CN     CN     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    CN     CN     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    CN     CN     H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    OCH.sub.3                                                                             OCH.sub.3                                                                             H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    OCH.sub.2 CH.sub.3                                                                    OCH.sub.2 CH.sub.3                                                                    H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2 0 H   H    SCH.sub.3                                                                             SCH.sub.3                                                                             H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    SCH.sub.3                                                                             SCH.sub.3                                                                             H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 H   H    SO.sub.2 CH.sub.3                                                                     SO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    SO.sub.2 CH.sub.3                                                                     SO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    H      H      CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2 0 H   H    H      H      CH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      H      CH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    H      H      CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 H   H    F      H      CH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 0 H   H    Cl     H      CH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   H    F      F      CH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   H    Br     H      CH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   H    Cl     Cl     CH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 0 H   5-CH.sub.3                                                                          H      H      --    OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 0 H   5-OCH.sub.3                                                                         H      H      --    CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2 0 H   5-SCH.sub.3                                                                         H      H      --    CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 0 H   5-Cl Cl     H      --    OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 0 H   6-Cl F      F      CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 0 CH.sub.3                                                                           H    H      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2 1 H   H    H      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 1 H   H    F      F      H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 1 H   H    F      Cl     H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 1 H   H    CH.sub.3                                                                              Cl     H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2 1 H   H    F      H      H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 1 H   H    Cl     H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 1 H   H    Br     H      H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 1 H   H    Cl     Cl     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 1 H   H    CH.sub.3                                                                              H      H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2 1 H   H    CH     H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 1 H   H    CH     CH     H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2 1 H   H    CH.sub.3                                                                              Br     H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2 1 H   H    F      Br     H     Cl  OCH.sub.3                                                                           CH                                 Q-2 1 H   5-CH.sub.3                                                                          F      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2 1 H   5-OCH.sub.3                                                                         Cl     H      CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2 1 H   5-Cl Cl     Cl     CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                           N                                  __________________________________________________________________________     Q  n R  R.sub.1                                                                             R.sub.3                                                                               R.sub.7                                                                            R.sub.8 R.sub.11                                                                            X   Y   Z  m.p.(°C.)               __________________________________________________________________________     Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CH.sub.3                                                                               H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CH.sub.3                                                                               H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CH.sub.3                                                                               H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CH.sub.3                                                                               H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   Cl      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   Cl      H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   Cl      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   Cl      H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   F       H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   F       H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   F       H    OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   F       H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   F       H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   F       H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CN      H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CN      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   OCH.sub.3                                                                              H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   OCH.sub.3                                                                              H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   OCH.sub.3                                                                              H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                      H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                      H    OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                      H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                      H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                      H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SO.sub.2 N(CH.sub.3).sub.2                                                             H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SO.sub.2 N(CH.sub.3).sub.2                                                             H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SO.sub.2 N(CH.sub.3).sub.2                                                             H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SO.sub.2 N(CH.sub.3).sub.2                                                             H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SCH.sub.3                                                                              H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SCH.sub.3                                                                              H    CH.sub.3                                                                           CH.sub.3                                                                           Cl                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SCH.sub.3                                                                              H    OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SCH.sub.3                                                                              H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SO.sub.2 CH.sub.3                                                                      H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SO.sub.2 CH.sub.3                                                                      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   SO.sub.2 CH.sub.3                                                                      H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              F   F       H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              F   F       H    OCH.sub.3                                                                          CH.sub.3                                                                           Cl                                Q-3                                                                               0 H  H    CH.sub.3                                                                              Cl  Cl      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              Cl  Cl      H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              F   Cl      H    OCH.sub.3                                                                          CH.sub.3                                                                           N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              F   CH.sub.3                                                                               H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                                                                               H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              F   Br      H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              Br  Br      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              CN  CN      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              CN  CN      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              CN  CN      H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                              H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       CH.sub.3                                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       CH.sub.3                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       OCH.sub.3                                                                           OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              H   H       CH.sub.2 CH.sub.3                                                                   OCH.sub.3                                                                          CH.sub.3                                                                           N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              F   H       CH.sub.3                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              Cl  H       CH.sub.3                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  H    CH.sub.3                                                                              F   F       CH.sub.3                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              Br  H       CH.sub.3                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  H    CH.sub.3                                                                              Cl  Cl      CH.sub.3                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  5-CH.sub.3                                                                          CH.sub.3                                                                              H   H       --   OCH.sub. 3                                                                         OCH.sub.3                                                                          N                                 Q-3                                                                               0 H  6-OCH.sub.3                                                                         CH.sub.3                                                                              H   H       --   CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0 H  3-SCH.sub.3                                                                         CH.sub.3                                                                              H   H       --   CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  5-Cl CH.sub.3                                                                              Cl  H       --   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0 H  6-Cl CH.sub.2 CH.sub.3                                                                     F   F       CH.sub.3                                                                            CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0 H  5-OCH.sub.2 F                                                                       CH.sub.2 CH.sub.3                                                                     Cl  H       H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0 CH.sub.3                                                                          H    CH.sub.2 CH.sub.3                                                                     H   H       H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               1 H  H    CH.sub.2 CH.sub.3                                                                     H   H       H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              F   F       H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              F   Cl      H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               1 H  H    CH.sub.2 CH.sub.3 CH.sub.3                                                            CH.sub.3                                                                           Cl      H    OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              F   H       H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              Cl  H       H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              Br  H       H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               1 H  H    CH.sub.2 CH.sub.3                                                                     Cl  Cl      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              CH.sub.3                                                                           H       H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              CN  H       H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              CN  CN      H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               1 H  H    CH.sub.3                                                                              CH.sub.3                                                                           Br      H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               1 H  H    CH.sub.3                                                                              F   Br      H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  3-CH.sub.3                                                                          CH.sub.3                                                                              F   H       H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               1 H  5-OCH.sub.3                                                                         CH.sub.3                                                                              Cl  H       CH.sub.3                                                                            CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               1 H  5-Cl CH.sub.3                                                                              Cl  Cl      CH.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           OCH.sub.3                                                                          N                                 __________________________________________________________________________     Q   n  R   R.sub.1                                                                               R.sub.7                                                                              R.sub.8 X     Y    Z   m.p.(°C.)                __________________________________________________________________________     Q-4 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH  197-199                         Q-4 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH  192-194                         Q-4 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH  194-196                         Q-4 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-4 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           N   155-158                         Q-4 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N   150-152                         Q-4 0  H   H      H     H       Cl    OCH.sub.3                                                                           CH  182-184                         Q-4 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-4 0  H   H      H     Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     Cl      Cl    OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-4 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-4 0  H   H      H     F       OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-4 0  H   H      H     F       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     F       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     F       Cl    OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-4 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-4 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-4 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     CO.sub.2 CH.sub.3                                                                      Cl    OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     OH      CH.sub.3                                                                             CH.sub.3                                                                            CH  148-150                         Q-4 0  H   H      H     OH      CH.sub.3                                                                             OCH.sub.3                                                                           CH  163-164                         Q-4 0  H   H      H     OH      OCH.sub.3                                                                            OCH.sub.3                                                                           CH  133-136                         Q-4 0  H   H      H     OH      CH.sub.3                                                                             OCH.sub.3                                                                           N   165-167                         Q-4 0  H   H      H     OH      OCH.sub.3                                                                            OCH.sub.3                                                                           N   160-162                         Q-4 0  H   H      H     OH      Cl    OCH.sub.3                                                                           CH  138-140                         Q-4 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     SCH.sub.3                                                                              CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-4 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-4 0  H   H      H     SCH.sub.3                                                                              Cl    OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-4 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 0  H   H      F     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-4 0  H   H      F     F       OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-4 0  H   H      Cl    Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      Cl    Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-4 0  H   H      F     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-4 0  H   H      F     CH.sub.3                                                                               CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-4 0  H   H      CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-4 0  H   H      Br    Br      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  H   H      OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   5-CH.sub.3                                                                            F     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 0  H   6-CH.sub.3                                                                            Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   3-CH.sub.3                                                                            Br    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 0  H   5-CH.sub.3                                                                            H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  H   5-OCH.sub.3                                                                           H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-4 0  H   6-SCH.sub.3                                                                           H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 0  H   5-Cl   Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 0  H   3-Cl   F     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-4 0  H   5-OCH.sub.2 F                                                                         Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 0  CH.sub.3                                                                           H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-4 1  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 1  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 1  H   H      F     Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-4 1  H   H      CH.sub.3                                                                             Cl      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-4 1  H   H      F     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 1  H   H      Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 1  H   H      Br    H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 1  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-4 1  H   H      CH.sub.3                                                                             H       CH.sub.3                                                                             OCH.sub. 3                                                                          CH                                  Q-4 1  H   H      CN    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 1  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-4 1  H   H      CH.sub.3                                                                             Br      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-4 1  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-4 1  H   5-CH.sub.3                                                                            F     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-4 1  H   5-OCH.sub.3                                                                           Cl    H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-4 1  H   5-Cl   Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-5 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     H       Cl    OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-5 0  H   H      H     Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     Cl      Cl    OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-5 0  H   H      H     F       OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-5 0  H   H      H     F       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     F       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     F       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     F       Cl    OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-5 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-5 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     CO.sub.2 CH.sub.3                                                                      Cl    OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     SCH.sub.3                                                                              CH.sub.3                                                                             CH.sub.3                                                                            Cl                                  Q-5 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-5 0  H   H      H     SCH.sub.3                                                                              Cl    OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     SO.sub.3 CH.sub.3                                                                      CH.sub. 3                                                                            CH.sub.3                                                                            CH                                  Q-5 0  H   H      H     SO.sub.3 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   H      H     SO.sub.3 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   H      F     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-5 0  H   H      F     F       OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-5 0  H   H      Cl    Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      Cl    Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 0  H   H      F     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-5 0  H   H      F     CH.sub.3                                                                               CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-5 0  H   H      CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-5 0  H   H      Br    Br      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      CO.sub.2 CH.sub.3                                                                    CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   H      OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   6-CH.sub.3                                                                            CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   3-CH.sub.3                                                                            CH.sub.3                                                                             H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 0  H   5-CH.sub.3                                                                            F     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   5-CH.sub.3                                                                            Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   6-CH.sub.3                                                                            Br    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 0  H   3-CH.sub.3                                                                            H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  H   5-OCH.sub.3                                                                           H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-5 0  H   5-SCH.sub.3                                                                           H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 0  H   5-Cl   Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 0  H   6-Cl   F     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 0  H   5-OCH.sub.2 F                                                                         Cl    F       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 0  CH.sub.3                                                                           H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-5 1  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 1  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 1  H   H      F     Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 1  H   H      CH.sub.3                                                                             Cl      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-5 1  H   H      F     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 1  H   H      Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 1  H   H      Br    H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 1  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 1  H   H      CH.sub.3                                                                             H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-5 1  H   H      CN    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 1  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-5 1  H   H      CH.sub.3                                                                             Br      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-5 1  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-5 1  H   3-CH.sub.3                                                                            F     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-5 1  H   5-OCH.sub.3                                                                           Cl    H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-5 1  H   6-Cl   Cl    H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     H       Cl    OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-6 0  H   H      H     Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     Cl      Cl    OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 0  H   H      H     F       OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-6 0  H   H      H     F       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     F       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     F       Cl    OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     CN      CH.sub.3                                                                             OCH.sub. 3                                                                          N                                   Q-6 0  H   H      H     CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-6 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     CO.sub.2 CH.sub.3                                                                      Cl    OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   H      H     SO.sub. 2 N(CH.sub.3).sub.2                                                            CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     SCH.sub.3                                                                              CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-6 0  H   H      H     SCH.sub.3                                                                              Cl    OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 0  H   H      F     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 0  H   H      F     F       OCH.sub.3                                                                            CH.sub.3                                                                            Cl                                  Q-6 0  H   H      Cl    Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      Cl    Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 0  H   H      F     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-6 0  H   H      F     CH.sub.3                                                                               CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 0  H   H      CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-6 0  H   H      Br    Br      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   H      OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   5-CH.sub.3                                                                            CH.sub.3                                                                             H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 0  H   6-CH.sub.3                                                                            F     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 0  H   3-CH.sub.3                                                                            Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   5-CH.sub.3                                                                            Br    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 0  H   6-CH.sub.3                                                                            H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  H   5-OCH.sub.3                                                                           H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 0  H   5-SCH.sub.3                                                                           H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 0  H   5-Cl   Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 0  H   3-Cl   F     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 0  H   5-OCH.sub.2 F                                                                         Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 0  CH.sub.3                                                                           H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-6 1  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 1  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 1  H   H      F     Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 1  H   H      CH.sub.3                                                                             Cl      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-6 1  H   H      F     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 1  H   H      Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 1  H   H      Br    H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 1  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 1  H   H      CH.sub.3                                                                             H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-6 1  H   H      CN    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 1  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-6 1  H   H      CH.sub.3                                                                             Br      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-6 1  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-6 1  H   3-CH.sub.3                                                                            F     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-6 1  H   3-OCH.sub.3                                                                           Cl    H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-6 1  H   5-Cl   Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-7 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     H       Cl    OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-7 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-7 0  H   H      H     Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     Cl      Cl    OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-7 0  H   H      H     F       OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-7 0  H   H      H     F       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     F       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     F       Cl    OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-7 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-7 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     CO.sub.2 CH.sub.3                                                                      Cl    OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     SCH.sub.3                                                                              CH.sub.3                                                                             CH.sub.3                                                                            Cl                                  Q-7 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-7 0  H   H      H     SCH.sub.3                                                                              Cl    OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-7 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   H      F     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-7 0  H   H      F     F       OCH.sub.3                                                                            CH.sub.3                                                                            Cl                                  Q-7 0  H   H      Cl    Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      Cl    Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 0  H   H      F     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-7 0  H   H      F     CH.sub.3                                                                               CH.sub.3                                                                             CH.sub. 3                                                                           CH                                  Q-7 0  H   H      CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-7 0  H   H      Br    Br      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   H      OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   3-CH.sub.3                                                                            CH.sub.3                                                                             H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   5-CH.sub.3                                                                            CH.sub.3                                                                             H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  CH.sub.3                                                                           H      CH.sub.3                                                                             H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 0  CH.sub.3                                                                           H      F     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   5-CH.sub.3                                                                            Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   H      Br    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 0  H   5-CH.sub.3                                                                            H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  H   6-OCH.sub.3                                                                           H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-7 0  H   5-SCH.sub.3                                                                           H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 0  H   3-Cl   Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 0  H   5-Cl   F     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 0  H   3-OCH.sub.2 F                                                                         Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 0  CH.sub.3                                                                           H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-7 1  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 1  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 1  H   H      F     Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 1  H   H      CH.sub.3                                                                             Cl      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-7 1  H   H      F     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 1  H   H      Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 1  H   H      Br    H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 1  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 1  H   H      CH.sub.3                                                                             H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-7 1  H   H      CN    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 1  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-7 1  H   H      CH.sub.3                                                                             Br      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-7 1  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-7 1  H   5-CH.sub.3                                                                            F     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-7 1  H   5-OCH.sub.3                                                                           Cl    H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-7 1  H   5-Cl   Cl    H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-8 0  H   H      H     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     H       Cl    OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     CH.sub.3                                                                               CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     Cl      OCH.sub.3                                                                            CH.sub. 3                                                                           N                                   Q-8 0  H   H      H     Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     Cl      Cl    OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-8 0  H   H      H     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     F       OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     F       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     F       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     F       Cl    OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     OCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-8 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub. 3                                                                          N                                   Q-8 0  H   H      H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     CO.sub.2 CH.sub.3                                                                      Cl    OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-8 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     SCH.sub.3                                                                              CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     SCH.sub.3                                                                              OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     SCH.sub.3                                                                              Cl    OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 0  H   H      F     F       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      F     F       OCH.sub.3                                                                            CH.sub.3                                                                            Cl                                  Q-8 0  H   H      Cl    Cl      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      Cl    Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-8 0  H   H      F     Cl      OCH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-8 0  H   H      F     CH.sub.3                                                                               CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-8 0  H   H      Br    Br      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   H      CN    CN      OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     Br      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   H      H     Br      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      H     Br      OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   3-CH.sub.3                                                                            CH.sub.3                                                                             H       CH.sub. 3                                                                            CH.sub.3                                                                            N                                   Q-8 0  H   5-CH.sub.3                                                                            F     H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 0  H   H      Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   H      Br    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 0  H   5-CH.sub.3                                                                            H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  H   5-OCH.sub.3                                                                           H     H       CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 0  H   5-SCH.sub.3                                                                           H     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 0  H   5-Cl   Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 0  H   6-Cl   F     F       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-8 0  H   5-OCH.sub.2 F                                                                         Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 0  CH.sub.3                                                                           H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-8 1  H   H      H     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 1  H   H      F     F       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 1  H   H      F     Cl      CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-8 1  H   H      CH.sub.3                                                                             Cl      OCH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-8 1  H   H      F     H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 1  H   H      Cl    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 1  H   H      Br    H       CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 1  H   H      Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 1  H   H      CH.sub.3                                                                             H       CH.sub.3                                                                             OCH.sub.3                                                                           CH                                  Q-8 1  H   H      CN    H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 1  H   H      CN    CN      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   Q-8 1  H   H      CH.sub.3                                                                             Br      CH.sub.3                                                                             CH.sub.3                                                                            CH                                  Q-8 1  H   H      F     Br      Cl    OCH.sub.3                                                                           CH                                  Q-8 1  H   5-CH.sub.3                                                                            F     H       OCH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-8 1  H   3-OCH.sub.3                                                                           Cl    H       CH.sub.3                                                                             CH.sub.3                                                                            N                                   Q-8 1  H   5-Cl   Cl    Cl      CH.sub.3                                                                             OCH.sub.3                                                                           N                                   __________________________________________________________________________     Q   n  R  R.sub.1                                                                              R.sub.3                                                                              R.sub.7                                                                            R.sub.8 X    Y   Z   m.p.(°C.)                __________________________________________________________________________     Q-9 0  H  H     CH.sub.3                                                                             H   H       CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   H       CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   H       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   H       CH.sub. 3                                                                           CH.sub.3                                                                           N                                   Q-9 0  H  H     CH.sub.3                                                                             H   H       CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   H       OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   H       Cl   OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   Cl      CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   Cl      OCH.sub.3                                                                           CH.sub.3                                                                           N                                   Q-9 0  H  H     CH.sub.3                                                                             H   Cl      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   Cl      Cl   OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   F       CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-9 0  H  H     CH.sub.3                                                                             H   F       CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   F       OCH.sub.3                                                                           CH.sub. 3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   F       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   F       CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   F       Cl   OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   CN      CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   CN      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-9 0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      OCH.sub. 3                                                                          OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-9 0  H  H     CH.sub.3                                                                             H   SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             H   SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SCH.sub.3                                                                              Cl   OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             F   F       CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             F   F       OCH.sub.3                                                                           CH.sub.3                                                                           Cl                                  Q-9 0  H  H     CH.sub.3                                                                             Cl  Cl      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             Cl  Cl      CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-9 0  H  H     CH.sub.3                                                                             F   Cl      OCH.sub.3                                                                           CH.sub.3                                                                           N                                   Q-9 0  H  H     CH.sub.3                                                                             F   CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             F   Br      Cl   OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             Br  Br      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             CN  CN      CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             CN  CN      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             CN  CN      OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   Br      CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   Br      CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             H   Br      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.2 CH.sub.3                                                                    H   H       CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-9 0  H  H     CH.sub.3                                                                             F   H       CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             Cl  H       OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             F   F       CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  H     CH.sub.3                                                                             Br  H       OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  H  H     CH.sub.3                                                                             Cl  Cl      CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 0  H  5-SCH.sub.3                                                                          CH.sub.3                                                                             H   H       CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 0  H  5-Cl  CH.sub.3                                                                             Cl  H       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 0  H  5-Cl  CH.sub.3                                                                             F   F       CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-9 0  H  5-OCH.sub.2 F                                                                        CH.sub.3                                                                             Cl  H       OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 0  CH.sub.3                                                                          H     CH.sub.3                                                                             H   H       OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-9 1  H  H     CH.sub.3                                                                             H   H       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 1  H  H     CH.sub.3                                                                             F   F       CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 1  H  H     CH.sub.3                                                                             F   Cl      CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-9 1  H  H     CH.sub.3                                                                             CH.sub.3                                                                           Cl      OCH.sub.3                                                                           CH.sub.3                                                                           CH                                  Q-9 1  H  H     CH.sub.3                                                                             F   H       CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 1  H  H     CH.sub.3                                                                             Cl  H       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 1  H  H     H     Br  H       CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 1  H  H     H     Cl  Cl      CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 1  H  H     H     CH.sub.3                                                                           H       CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-9 1  H  H     H     CN  H       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 1  H  H     H     CN  CN      CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-9 1  H  H     H     CH.sub.3                                                                           Br      CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-9 1  H  H     H     F   Br      Cl   OCH.sub.3                                                                          CH                                  Q-9 1  H  3-CH.sub.3                                                                           H     F   H       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-9 1  H  6-OCH.sub.3                                                                          CH.sub.3                                                                             Cl  H       CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-9 1  H  5-Cl  CH.sub.2 CH.sub.3                                                                    Cl  Cl      CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   H       CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   H       CH.sub. 3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   H       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   H       CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   H       CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   H       OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   H       Cl   OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   Cl      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   Cl      OCH.sub.3                                                                           CH.sub.3                                                                           N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   Cl      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   Cl      Cl   OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   F       CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   F       CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   F       OCH.sub.3                                                                           CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   F       OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   F       CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   F       Cl   OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CN      CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CN      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SCH.sub.3                                                                              Cl   OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             H   SO.sub.2 CH.sub. 3                                                                     CH.sub.3                                                                            OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             F   F       CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             F   F       OCH.sub.3                                                                           CH.sub.3                                                                           Cl                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             Cl  Cl      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             Cl  Cl      CH.sub.3                                                                            CH.sub.3                                                                           N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             F   Cl      OCH.sub.3                                                                           CH.sub.3                                                                           N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             F   CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                           CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                          H                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             F   Br      Cl   OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             Br  Br      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             CN  CN      CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             CN  CN      OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                  Q-10                                                                               0  H  H     CH.sub.3                                                                             CN  CN      OCH.sub.3                                                                           OCH.sub.3                                                                          N                                   Q-10                                                                               0  H  H     CH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                          CH                                  __________________________________________________________________________     Q    n R   R.sub.1                                                                             R.sub.7                                                                            R.sub.8                                                                            R.sub.3   X   Y    Z   m.p.(°C.)                __________________________________________________________________________     Q-10                                                                               0  H   H    H   Br  CH.sub.3  CH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-10                                                                               0  H   H    H   Br  CH.sub.3  CH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                               0  H   H    H   Br  CH.sub.3  OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                  Q-10                                                                               0  H   H    H   H   CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                      OCH.sub.3                                                                          CH.sub.3                                                                            N                                   Q-10                                                                               0  H   5-CH.sub.3                                                                          F   H   CH.sub.3  CH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                               0  H   H    Cl  H   CH.sub.3  OCH.sub.3                                                                          OCH.sub.3                                                                           N                                   Q-10                                                                               0  H   H    F   F   CH.sub.3  CH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                               0  H   H    Br  H   CH.sub.3  OCH.sub.3                                                                          OCH.sub.3                                                                           N                                   Q-10                                                                               0  H   H    Cl  Cl  CH.sub.3  CH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                               0  H   6-CH.sub.3                                                                          H   H   CH.sub.2 CH.sub.2 CH.sub.3                                                               OCH.sub.3                                                                          OCH.sub.3                                                                           N                                   Q-10                                                                               0  H   5-OCH.sub.3                                                                         H   H   CH.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-10                                                                               0  H   3-SCH.sub.3                                                                         H   H   CH.sub.2 CH.sub.2 CH.sub.3                                                               CH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                               0  H   6-Cl Cl  H   CH.sub.2 CH.sub.3                                                                        OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                  Q-10                                                                               0  H   5-Cl F   F   CH.sub.3  CH.sub.3                                                                           CH.sub.3                                                                            N                                   Q-10                                                                               0  H   5-OCH.sub.2 F                                                                       Cl  H   CH.sub.3  OCH.sub.3                                                                          OCH.sub.3                                                                           N                                   Q-10                                                                               0  CH.sub.3                                                                           H    H   H   H         OCH.sub.3                                                                          OCH.sub.3                                                                           N                                   Q-10                                                                               1  H   H    H   H   H         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   H    F   F   H         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   H    F   Cl  CH.sub.3  CH.sub.3                                                                           CH.sub.3                                                                            N                                   Q-10                                                                               1  H   H    CH.sub.3                                                                           Cl  H         OCH.sub.3                                                                          CH.sub.3                                                                            CH                                  Q-10                                                                               1  H   H    F   H   H         CH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   H    Cl  H   CH.sub.3  OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   H    Br  H   H         CH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                               1  H   H    Cl  Cl  CH.sub.3  CH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   H    CH.sub.3                                                                           H   CH.sub.3  CH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   H    CN  H   CH.sub.3  OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   H    CN  CN  H         CH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                               1  H   H    CH.sub.3                                                                           Br  H         CH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-10                                                                               1  H   H    F   Br  CH.sub.3  Cl  OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   3-CH.sub.3                                                                          F   H   H         OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                  Q-10                                                                               1  H   5-OCH.sub.3                                                                         Cl  H   CH.sub.3  CH.sub.3                                                                           CH.sub.3                                                                            N                                   Q-10                                                                               1  H   6-Cl Cl  Cl  CH.sub.2 CH.sub.3                                                                        CH.sub.3                                                                           OCH.sub.3                                                                           N                                   __________________________________________________________________________     Q  n R R.sub.1                                                                          R.sub.3                                                                           R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                           R.sub.10                                                                          R.sub.11                                                                          X        Y        Z  m.p.(°C.)               __________________________________________________________________________     Q-1                                                                               0 H H -- H  H  H  H  -- NHCH.sub.3                                                                              OCH.sub.2 CH.sub.3                                                                      N  203-206                        Q-1                                                                               0 H H -- H  H  H  H  -- CH.sub.3 SCH.sub.3                                                                               CH                                Q-1                                                                               0 H H -- H  H  Cl H  -- N(CH.sub.3)H                                                                            OCH.sub.2 CH.sub.3                                                                      N  154-158                        Q-1                                                                               0 H H -- Cl Cl H  H  -- OCH.sub.3                                                                               CH(OCH.sub.3).sub.2                                                                     CH                                Q-1                                                                               0 H H -- CH.sub.3                                                                          H  H  H  -- OCH.sub.3                                                                               OCH.sub.2 CHCH.sub.                                                                     CH                                Q-1                                                                               0 H H -- CH.sub.3                                                                          H  H  Cl -- OCH.sub.2 CH.sub.3                                                                      CH                                         Q-1                                                                               0 H H -- F  F  H  H  -- OCH.sub.2 CH.sub.3                                                                      OCH.sub.2 F                                                                             N                                 Q-1                                                                               0 H H -- H  CN H  H  -- OCH.sub.3                                                                               SCH.sub.3                                                                               CH                                Q-1                                                                               0 H Cl                                                                               -- Br H  H  CH.sub.3                                                                          -- OCH.sub.3                                                                               Br       CH                                Q-1                                                                               0 H H -- H  Br H  H  -- OCH.sub.3                                                                               NH.sub.2 CH                                Q-1                                                                               0 H H -- H  Br Cl H  -- OCH.sub.3                                                                               NHCH.sub.3                                                                              N                                 Q-1                                                                               0 H H -- F  F  Cl F  -- CH.sub.3 OCH.sub.2 CCH                                                                           CH                                Q-1                                                                               0 H H -- F  CN H  H  -- OCH.sub.3                                                                               CH.sub.2 CF.sub.3                                                                       CH                                Q-1                                                                               0 H H -- H  H  H  H  -- OCF.sub.2 CH.sub.3                                                                      CH.sub.3 N                                 Q-1                                                                               0 H H -- H  H  H  H  -- OCH.sub.3                                                                               CCH      CH                                Q-1                                                                               0 H H -- Cl Cl H  H  -- OCH.sub.3                                                                                ##STR48##                                                                              CH                                Q-2                                                                               0 H H -- H  H  H  H  H  OCH.sub.3                                                                               OCH.sub.2 CH.sub.3                                                                      N                                 Q-2                                                                               0 H H -- Cl H  H  H  H  CH.sub.3 OCH.sub.3                                                                      CH.sub.2 CF.sub.3                                                                       N                                 Q-2                                                                               0 H H -- Cl H  CH.sub.3                                                                          H  H  OCH.sub.3                                                                               N(CH.sub.3).sub.2                                                                       N                                 Q-4                                                                               0 H H -- H  H  H  H  -- CH.sub.3 CH.sub.2 CH.sub.3                                                                       CH                                Q-4                                                                               0 H H -- H  H  H  H  -- OCH.sub.3                                                                               OCH.sub.2 OCH.sub.3                                                                     CH                                Q-5                                                                               0 H H -- Cl H  H  H  -- OCH.sub.3                                                                               SCH.sub.2 CH.sub.3                                                                      CH                                Q-5                                                                               0 H H -- Cl Cl H  H  -- OCF.sub.2 H                                                                             CH.sub.2 CH.sub.3                                                                       CH                                Q-5                                                                               0 H H -- CH.sub.3                                                                          H  H  CH.sub.3                                                                          -- OCH.sub.3                                                                               F        CH                                Q-9                                                                               0 H H CH.sub.3                                                                          H  H  H  H  -- SCH.sub.2 CH.sub.2 F                                                                    HNCH.sub.3                                                                              CH                                Q-9                                                                               0 H H H  H  H  H  F  -- OCH.sub.3                                                                               OCH.sub.2 CHCH.sub.2                                                                    CH                                Q-3                                                                               0 H H CH.sub.3                                                                          H  H  H  H  H  OCH.sub.2 CH.sub.3                                                                      SCH.sub.2 CH.sub.3                                                                      N                                 Q-3                                                                               0 H H CH.sub.3                                                                          F  H  H  Br CH.sub.3                                                                          OCH.sub.3                                                                               I        CH                                Q-3                                                                               0 H H H  H  H  H  H  H  OCH.sub.2 OCH.sub.2 CH.sub.3                                                            CH.sub.3 CH                                Q-7                                                                               0 H H -- H  H  H  H  -- OCH.sub.2 OCH.sub.2 CH.sub.3                                                            OCH.sub.3                                                                               N                                 Q-7                                                                               0 H H -- H  H  H  H  -- OCHF.sub.2                                                                              N(CH.sub.3).sub.2                                                                       CH                                Q-7                                                                               0 H H -- Cl H  H  H  -- OCH.sub.3                                                                               N(OCH.sub.3)CH.sub.3                                                                    N                                 __________________________________________________________________________     General Structure I (wherein R.sub.12 and R.sub.13 are H) (W = S)              Q  n  R R.sub.1                                                                             R.sub.7                                                                             R.sub.8 R.sub.9                                                                          R.sub.10                                                                           R.sub.11                                                                          X    Y   Z   m.p.(°C.)               __________________________________________________________________________     Q-1                                                                               0  H H    H    H       H H   -- CH.sub.3                                                                            CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    H    H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    H       H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H 5-CH.sub.3                                                                          H    H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H    H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H    H       H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H    H       H H   -- Cl   OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    F       H H   -- CH.sub.3                                                                            CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    H    F       H H   -- CH.sub.3                                                                            CH.sub.3                                                                           N                                  Q-1                                                                               0  H H    H    F       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    Cl      H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    Cl      H H   -- CH.sub.3                                                                            CH.sub.3                                                                           N                                  Q-1                                                                               0  H H    Cl   H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    Cl   H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H    Br      H H   -- CH.sub.3                                                                            CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    Br   H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    Br   H       H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    I       H H   -- CH.sub.3                                                                            CH.sub.3                                                                           N                                  Q-1                                                                               0  H H    I    H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H    CN      H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    CN   H       H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    CH.sub.3                                                                               H H   -- CH.sub.3                                                                            CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    H    CH.sub.3                                                                               H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    CH.sub.3                                                                               H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    CH.sub.3                                                                            H       H H   -- Cl   OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    CH.sub.3                                                                            H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H    CH.sub.2 CH.sub.3                                                                      H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    CH.sub. 2 CH.sub.3                                                                  H       H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    CH.sub.2 CH.sub.3                                                                      H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H    CH.sub.2 CH.sub.2 CH.sub.3                                                             H H   -- CH.sub.3                                                                            OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H    Cl      H H   -- CH.sub.3                                                                            CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    H    Cl      H H   -- OCH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H    Cl      H H   -- Cl   OCH.sub.3                                                                          CH                                 __________________________________________________________________________

                                      TABLE IA                                     __________________________________________________________________________     General Structure I (wherein R.sub.12 is OH; R.sub.13 is H)                    Q  n R R.sub.1                                                                          R.sub.7                                                                            R.sub.8                                                                               R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  m.p. (°C.)                       __________________________________________________________________________     Q-1                                                                               1 H H H   H      H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH 148-150                                 Q-1                                                                               1 H H H   H      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH 140-142                                 Q-1                                                                               1 H H H   H      H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH 148-150                                 Q-1                                                                               1 H H H   H      H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H   H      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N  109-111                                 Q-1                                                                               1 H H H   H      H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N  147-149                                 Q-1                                                                               1 H H H   H      H H  -- Cl  OCH.sub.3                                                                          CH 124-126                                 Q-1                                                                               1 H H H   F      H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H   F      H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H   F      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   Cl     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   Cl     H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H Cl  H      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl  H      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   Br     H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H Br  H      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br  H      H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   I      H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H I   H      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CN     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H CN  H      H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   CH.sub.3                                                                              H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H   CH.sub.3                                                                              H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   CH.sub.3                                                                              H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CH.sub.3                                                                           H      H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H CH.sub.3                                                                           H      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CH.sub.2 CH.sub.3                                                                     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CH.sub.2 CH.sub.3                                                                     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   CH.sub.2 CH.sub.2 CH.sub.3                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   OCH.sub.3                                                                             H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H   OCH.sub.3                                                                             H H  -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H CH.sub.3 O                                                                         H      H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   OCH.sub.2 CH.sub.3                                                                    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H   CO.sub.2 CH.sub.3                                                                     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CO.sub.2 CH.sub.3                                                                     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CO.sub.2 CH.sub.3                                                                     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   CO.sub.2 CH.sub.3                                                                     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   CO.sub.2 CH.sub.2 CH.sub.3                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   SO.sub.2 N(CH.sub.3).sub.2                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   SO.sub.2 N(CH.sub.3).sub.2                                                            H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H   SCH.sub.3                                                                             H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   SCH.sub.3                                                                             H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H H  -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   SO.sub.2 CH.sub.2 CH.sub.3                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   CH.sub.3                                                                              H CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CH.sub.3                                                                              H CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CH.sub.3                                                                              CH.sub.3                                                                         H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H   CH.sub.3                                                                              H F  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   CH.sub.3                                                                              H F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   CH.sub.3                                                                              H F  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CH.sub.3                                                                              H Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   CH.sub.3                                                                              Br                                                                               H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   F      H CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   F      H CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   Cl     H CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   Cl     H F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   Cl     H Cl -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   Cl     H Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   Cl     H Br -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H CH.sub.3                                                                          -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H CH.sub.3                                                                          -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H Cl -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H   SO.sub.2 CH.sub.3                                                                     H Br -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H F   F      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H F   F      H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H F   F      H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H F   F      H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H F   F      H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H F   F      H H  -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl  Cl     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl  Cl     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl  Cl     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl  Cl     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl  Cl     H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H Cl  Cl     H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H Cl  Cl     H H  -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br  Br     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br  Br     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br  Br     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br  Br     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br  Br     H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H I   I      H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN  CN     H H  -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN  CN     H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H CN  CN     H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H F   F      H CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H F   F      H CH.sub.3                                                                          -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H F   F      H F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H F   F      H Cl -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H F   F      H Br -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl  Cl     H CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl  Cl     H CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl  Cl     H Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl  Cl     H F  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl  Cl     H Br -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br  Br     H CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H Br  Br     H CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br  Br     H Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br  Br     H Cl -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H Br  Br     Cl                                                                               H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br  Br     H F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br  Br     H Br -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN  CN     H CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN  CN     H CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN  CN     H F  -- CH.sub. 3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H CH.sub.3                                                                           CH.sub.3                                                                              H CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H CH.sub.3                                                                           CH.sub.3                                                                              H CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H CH.sub.3                                                                           CH.sub.3                                                                              H CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CH.sub.3                                                                           CH.sub.3                                                                              CH.sub.3                                                                         H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         __________________________________________________________________________

                                      TABLE IB                                     __________________________________________________________________________     General Structure I (wherein R.sub.12 is OH; R.sub.13 is CH.sub.3)             Q  n R R.sub.1                                                                          R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  m.p. (°C.)                            __________________________________________________________________________     Q-1                                                                               1 H H H  H  H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                              Q-1                                                                               1 H H H  H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  H  H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  H  H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                               Q-1                                                                               1 H H H  H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H H  H  H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H H  H  H H  -- Cl  OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  F  H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                              Q-1                                                                               1 H H H  F  H H  -- CH.sub.3                                                                           CH.sub. 3                                                                          N                                               Q-1                                                                               1 H H H  F  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  Cl H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  Cl H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                               Q-1                                                                               1 H H Cl H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H Cl H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H H  Br H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                              Q-1                                                                               1 H H Br H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H Br H  H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  I  H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                               Q-1                                                                               1 H H I  H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H H  CN H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H CN H  H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  CH.sub.3                                                                          H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                              __________________________________________________________________________

                                      TABLE IC                                     __________________________________________________________________________     General Structure I (wherein R.sub.12 is OCH.sub.3 ; R.sub.13 is H)            Q  n R R.sub.1                                                                          R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  m.p. (°C.)                            __________________________________________________________________________     Q-1                                                                               1 H H H  H  H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                              Q-1                                                                               1 H H H  H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  H  H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  H  H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                               Q-1                                                                               1 H H H  H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H H  H  H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H H  H  H H  -- Cl  OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  F  H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                              Q-1                                                                               1 H H H  F  H H  -- CH.sub.3                                                                           CH.sub. 3                                                                          N                                               Q-1                                                                               1 H H H  F  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  Cl H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  Cl H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                               Q-1                                                                               1 H H Cl H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H Cl H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H H  Br H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                              Q-1                                                                               1 H H Br H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H Br H  H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  I  H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                               Q-1                                                                               1 H H I  H  H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H H  CN H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               Q-1                                                                               1 H H CN H  H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              Q-1                                                                               1 H H H  CH.sub.3                                                                          H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                              __________________________________________________________________________

                  TABLE ID                                                         ______________________________________                                         General Structure I (wherein R.sub.12 is OH; R.sub.13 is CH.sub.3)                                                              m.p.                          Q    n     R     R.sub.1                                                                            R.sub.7                                                                            R.sub.8                                                                               X     Y     Z    (°C.)                  ______________________________________                                         Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   F      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CN     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CN     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     Cl    OCH.sub.3                                                                            CH                                 ______________________________________                                    

                  TABLE IE                                                         ______________________________________                                         General Structure I (wherein R.sub.12 is OH; R.sub.13 is CH.sub.3)                                                              m.p.                          Q    n     R     R.sub.1                                                                            R.sub.7                                                                            R.sub.8                                                                               X     Y     Z    (°C.)                  ______________________________________                                         Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.                                                                             CH                                 Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   F      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CN     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CN     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   CO.sub. CH.sub.3                                                                      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     Cl    OCH.sub.3                                                                            CH                                 ______________________________________                                    

                  TABLE IF                                                         ______________________________________                                         General Structure I (wherein R.sub.12 is OCH.sub.3 ; R.sub.13 is H)                                                             m.p.                          Q    n     R     R.sub.1                                                                            R.sub.7                                                                            R.sub.8                                                                               X     Y     Z    (°C.)                  ______________________________________                                         Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   F      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CN     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CN     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     Cl    OCH.sub.3                                                                            CH                                 ______________________________________                                    

                  TABLE IG                                                         ______________________________________                                         General Structure I (wherein R.sub.12 is OCH.sub.3 ; R.sub.13 is               CH.sub.3)                                                                                                                       m.p.                          Q    n     R     R.sub.1                                                                            R.sub.7                                                                            R.sub.8                                                                               X     Y     Z    (°C.)                  ______________________________________                                         Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     CH.sub.3                                                                             OCH.sub. 3                                                                           CH                                 Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   F      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CN     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CN     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     Cl    OCH.sub.3                                                                            CH                                 ______________________________________                                    

                                      TABLE II                                     __________________________________________________________________________     General Structure II (wherein R.sub.12 and R.sub.13 are H)                                                                                 m.p.               L  Q.sub.1                                                                           n  R  R.sub.1                                                                            R.sub.2                                                                           R.sub.3                                                                               R.sub.2 R.sub.3                                                                   R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                           R.sub.10                                                                           R.sub.11                                                                           X   Y   Z   (°C.)       __________________________________________________________________________     L-2                                                                               Q-1                                                                               0  H  H   --           H  H    H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-1                                                                               0  H  H   --           H  Cl   H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               0  H  H   --           Cl Cl   H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               0  H  H   --           F  F    H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-1                                                                               0  H  H   --           H  Br   H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-1                                                                               0  H  H   --           CH.sub.3                                                                          H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-1                                                                               0  H  H   --           H  OCH.sub.3                                                                           H  H   --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               0  H  H   --           H  F    H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               0  H  H   --           Cl Br   H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               0  H  H   --           Cl CH.sub.3                                                                            H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-1                                                                               0  H  H   --           F  CH.sub.3                                                                            H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               0  H  H   --           H  Cl   Cl H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-1                                                                               0  H  H   --           H  CH.sub.3                                                                            F  F   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               0  H  CH.sub.3                                                                           --           H  H    H  H   --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               0  CH.sub.3                                                                          H   --           H  H    H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-1                                                                               1  H  H   --           F  F    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-1                                                                               1  H  H   --           H  H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               0  H  H   --           H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-2                                                                               0  H  H   --           H  H    -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2                                                                               Q-2                                                                               0  H  H   --           H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               0  H  H   --           Cl H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-2                                                                               0  H  H   --           F  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               0  H  H   --           H  Br   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               0  H  H   --           F  F    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-2                                                                               0  H  H   --           Cl Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               0  H  H   --           H  CH.sub.3                                                                            -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               0  H  H   --           CH.sub.3                                                                          CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               0  H  H   --           H  CO.sub.2 CH.sub.3                                                                   -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-2                                                                               0  H  H   --           H  F    -- --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               0  H  OCH.sub.3                                                                          --           H  Cl   -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2                                                                               Q-2                                                                               0  CH.sub.3                                                                          Cl  --           F  CH.sub.3                                                                            -- --  CH.sub.3                                                                           CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               1  H  H      --        H  Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-2                                                                               1  H  H      --        Cl Cl   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-2                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  H   Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  F  F    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Br   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  CH.sub.3                                                                          H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  OCH.sub.3                                                                           -- --  H   Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  F    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Br   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl CH.sub.3                                                                            -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Cl   -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  H  CH.sub.3                                                                              CH.sub.3  H  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               0  CH.sub.3                                                                          H      CH.sub.3  H  H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-3                                                                               1  H  H      CH.sub.3  F  F    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-3                                                                               1  H  H      CH.sub.3  H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-4                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-4                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-4                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2                                                                               Q-4                                                                               0  CH.sub.3                                                                          Cl  --           F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               1  H  H   --           H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-4                                                                               1  H  H   --           Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-4                                                                               1  H  H   --           F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               0  H  H   --           H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-5                                                                               0  H  H   --           H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.                                                                           CH                     L-2                                                                               Q-5                                                                               0  H  H   --           Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               0  H  H   --           F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-5                                                                               0  H  H   --           H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-5                                                                               0  H  H   --           CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-5                                                                               0  H  H   --           H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               0  H  H   --           H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               0  H  H   --           Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               0  H  H   --           Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-5                                                                               0  H  H   --           F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               0  H  H   --           H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-5                                                                               0  H  H   --           H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               0  H  CH.sub.3                                                                           --           H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               0  CH.sub.3                                                                          H   --           H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-5                                                                               1  H  H   --           F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-5                                                                               1  H  H   --           H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               0  H  H   --           H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-6                                                                               0  H  H   --           H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2                                                                               Q-6                                                                               0  H  H   --           H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               0  H  H   --           Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-6                                                                               0  H  H   --           F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               0  H  H   --           H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               0  H  H   --           F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-6                                                                               0  H  H   --           Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               0  H  H   --           H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               0  H  H   --           CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               0  H  H   --           H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-6                                                                               0  H  H   --           H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               0  H  OCH.sub.3                                                                          --           H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2                                                                               Q-6                                                                               0  CH.sub.3                                                                          Cl  --           F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               1  H  H   --           H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-6                                                                               1  H  H   --           Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-6                                                                               1  H  H   --           F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  H  H   --           H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-7                                                                               0  H  H   --           H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  H  H   --           Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  H  H   --           F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-7                                                                               0  H  H   --           H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-7                                                                               0  H  H   --           CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-7                                                                               0  H  H   --           H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  H  H   --           H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  H  H   --           Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  H  H   --           Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-7                                                                               0  H  H   --           F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  H  H   --           H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-7                                                                               0  H  H   --           H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  H  CH.sub.3                                                                           --           H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               0  CH.sub.3                                                                          H   --           H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-7                                                                               1  H  H   --           F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-7                                                                               1  H  H   --           H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               0  H  H   --           H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-8                                                                               0  H  H   --           H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2                                                                               Q-8                                                                               0  H  H   --           H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               0  H  H   --           Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-8                                                                               0  H  H   --           F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               0  H  H   --           H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               0  H  H   --           F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-8                                                                               0  H  H   --           Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               0  H  H   --           H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               0  H  H   --           CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-8                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2                                                                               Q-8                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-8                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-8                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  CH.sub. 3                                                                         H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  H  CH.sub.3                                                                              CH.sub.3  H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               0  CH.sub.3                                                                          H      CH.sub. 3 H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-9                                                                               1  H  H      CH.sub.3  F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-9                                                                               1  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              0  H  H      CH.sub.3  Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-10                                                                              0  H  H      CH.sub.3  Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              0  H  H             CH.sub.3                                                                          H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              0  H  H             CH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              0  H  H             CH.sub.3                                                                          H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2                                                                               Q-10                                                                              0  H  H             CH.sub.3                                                                          H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              0  H  OCH.sub.3     CH.sub.3                                                                          H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2                                                                               Q-10                                                                              0  CH.sub.3                                                                          Cl            CH.sub.3                                                                          F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              1  H  H             CH.sub.3                                                                          H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2                                                                               Q-10                                                                              1  H  H             CH.sub.3                                                                          Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2                                                                               Q-10                                                                              1  H  H             CH.sub.3                                                                          F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          H  H    H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          H  Cl   H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          Cl Cl   H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          F  F    H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          H  Br   H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          CH.sub.3                                                                          H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          H  OCH.sub.3                                                                           H  H   --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          H  F    H  H   --  CH.sub.3                                                                           OCH.sub.                                                                           CH                     L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          Cl Br   H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          Cl CH.sub.3                                                                            H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          F  CH.sub.3                                                                            H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          H  Cl   Cl H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-1                                                                               0  H  H             CH.sub.3                                                                          H  CH.sub.3                                                                            F  F   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               0  H  CH.sub.3      CH.sub.3                                                                          H  H    H  H   --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               0  CH.sub.3                                                                          H             CH.sub.3                                                                          H  H    H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-1                                                                               1  H  H             CH.sub.3                                                                          F  F    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-1                                                                               1  H  H             CH.sub.3                                                                          H  H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               0  H  H             CH.sub.3                                                                          H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-2                                                                               0  H  H             CH.sub.3                                                                          H  H    -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3                                                                               Q-2                                                                               0  H  H             CH.sub.3                                                                          H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               0  H  H             CH.sub.3                                                                          Cl H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-2                                                                               0  H  H             CH.sub.3                                                                          F  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               0  H  H             CH.sub.3                                                                          H  Br   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               0  H  H   CH.sub.3                                                                          --        F  F       --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-2                                                                               0  H  H   CH.sub.3                                                                          --        Cl Cl      --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               0  H  H   CH.sub.3                                                                          --        H  CH.sub.3                                                                               --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               0  H  H   CH.sub.3                                                                          --        CH.sub.3                                                                          CH.sub.3                                                                               --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               0  H  H   CH.sub.3                                                                          --        H  CO.sub.2 CH.sub.3                                                                      --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-2                                                                               0  H  H   CH.sub.3                                                                          --        H  F       --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               0  H  OCH.sub.3                                                                          CH.sub.3                                                                          --        H  Cl      --  H   OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3                                                                               Q-2                                                                               0  CH.sub.3                                                                          Cl  CH.sub.3                                                                          --        F  CH.sub.3                                                                               --  CH.sub.3                                                                           CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               1  H  H   CH.sub.3                                                                          --        H  Cl      --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-2                                                                               1  H  H   CH.sub.3                                                                          --        Cl Cl      --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-2                                                                               1  H  H   CH.sub.3                                                                          --        F  CH.sub.3                                                                               --  H   Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  H       --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  Cl      --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  Cl Cl      --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  F  F       --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  Br      --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  CH.sub.3                                                                          H       --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  OCH.sub.3                                                                              --  H   Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  F       --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  Cl Br      --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  Cl CH.sub.3                                                                               --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  F  CH.sub.3                                                                               --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                        H  Cl      --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-3                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  CH.sub.3                                                                               --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  H  CH.sub.3                                                                           CH.sub.3                                                                          CH.sub.3  H  H       --  H   Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               0  CH.sub.3                                                                          H   CH.sub.3                                                                          CH.sub.3  H  H       --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-3                                                                               1  H  H   CH.sub.3                                                                          CH.sub.3  F  F       --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-3                                                                               1  H  H   CH.sub.3                                                                          CH.sub.3  H  H       --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3                                                                          --        H  H       --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3                                                                          --        H  H       --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3                                                                          --        H  H       --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3                                                                          --        Cl H       --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3     F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3     H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3     F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3     Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3     H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3     CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3     H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-4                                                                               0  H  H   CH.sub.3     H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               0  H  OCH.sub.3                                                                          CH.sub.3     H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3                                                                               Q-4                                                                               0  CH.sub.3                                                                          Cl  CH.sub.3     F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               1  H  H   CH.sub.3     H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-4                                                                               1  H  H   CH.sub.3     Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-4                                                                               1  H  H   CH.sub.3     F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-5                                                                               0  H  H   CH.sub.3     H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  H  CH.sub.3                                                                           CH.sub.3     H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               0  CH.sub.3                                                                          H   CH.sub.3     H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-5                                                                               1  H  H   CH.sub.3     F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-5                                                                               1  H  H   CH.sub.3     H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-6                                                                               0  H  H   CH.sub.3     H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               0  H  OCH.sub.3                                                                          CH.sub.3     H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3                                                                               Q-6                                                                               0  CH.sub.3                                                                          Cl  CH.sub.3     F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               1  H  H   CH.sub.3     H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-6                                                                               1  H  H   CH.sub.3     Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-6                                                                               1  H  H   CH.sub.3     F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-7                                                                               0  H  H   CH.sub. 3    H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-7                                                                               0  H  H   CH.sub.3     H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  H  CH.sub.3                                                                           CH.sub.3     H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               0  CH.sub.3                                                                          H   CH.sub.3     H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-7                                                                               1  H  H   CH.sub.3     F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-7                                                                               1  H  H   CH.sub.3     H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        H  H    --     --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        H  H    --     --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        H  H    --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        Cl H    --     --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        F  H    --     --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        H  Br   --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        F  F    --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        Cl Cl   --     --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        H  CH.sub.3                                                                            --     --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        CH.sub.3                                                                          CH.sub.3                                                                            --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        CH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                   --     --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-8                                                                               0  H  H   CH.sub.3                                                                          --        H  F    --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               0  H  OCH.sub.3                                                                          CH.sub.3                                                                          --        H  Cl   --     --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3                                                                               Q-8                                                                               0  CH.sub.3                                                                          Cl  CH.sub.3                                                                          --        F  CH.sub.3                                                                            --     --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               1  H  H   CH.sub.3                                                                          --        H  Cl   --     --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-8                                                                               1  H  H   CH.sub.3                                                                          --        Cl Cl   --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-8                                                                               1  H  H   CH.sub.3                                                                          --        F  CH.sub.3                                                                            --     --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  H    --     --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  Cl   --     --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  Cl Cl   --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  F  F    --     --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  Br   --     --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  CH.sub.3                                                                          H    --     148 --                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  OCH.sub.3                                                                           --     --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  F    --     --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  Cl Br   --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  Cl CH.sub.3                                                                            --     --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  F  CH.sub.3                                                                            --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.3  H  Cl   --     --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3                                                                               Q-9                                                                               0  H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                        H  CH.sub.3                                                                            --     --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  H  CH.sub.3                                                                           CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                        H  H    --     --  Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               0  CH.sub.3                                                                          H   CH.sub.3                                                                          CH.sub.2 CH.sub.2 CH.sub.3                                                               H  H    --     --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-9                                                                               1  H  H   CH.sub.3                                                                          CH.sub.3  F  F    -- --      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-9                                                                               1  H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                        H  H    -- --      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  H  H    -- --      CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  H  H    -- --      OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  H  H    -- --      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  Cl H    -- --      CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  F  H    -- --      Cl  OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  H  Br   -- --      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  F  F    -- --      OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  Cl Cl   -- --      CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  H  CH.sub.3                                                                            -- --      CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  CH.sub.3                                                                          CH.sub.3                                                                            -- --      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  H  CO.sub.2 CH.sub.3                                                                   -- --      CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3                                                                               Q-10                                                                              0  H  H   CH.sub.3                                                                          CH.sub.3  H  F    -- --      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              0  H  OCH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3  H  Cl   -- --      OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3                                                                               Q-10                                                                              0  CH.sub.3                                                                          Cl  CH.sub.3                                                                          CH.sub.3  F  CH.sub.3                                                                            -- --      CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              1  H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                        H  Cl   -- --      CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3                                                                               Q-10                                                                              1  H  H   CH.sub.3                                                                          CH.sub.3  Cl Cl   -- --      OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3                                                                               Q-10                                                                              1  H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                        F  CH.sub.3                                                                            -- --      Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               0  H  H   -- --        H  H    H  H       CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-1                                                                               0  H  H   -- --        Cl Cl   H  H       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               0  H  H   -- --        F  F    H  H       CH.sub.                                                                            CH.sub.3                                                                           N                      L-4                                                                               Q-1                                                                               0  H  H   -- --        H  Br   H  H       CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-1                                                                               0  H  H   -- --        CH.sub.3                                                                          Br   H  H       OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-1                                                                               0  H  H   -- --        H  OCH.sub.3                                                                           H  H       Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               0  H  H   -- --        H  F    H  H       CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               0  H  H   -- --        Cl Br   H  H       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               0  H  H   -- --        Cl CH.sub.3                                                                            H  H       CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-1                                                                               0  H  H   -- --        F  CH.sub.3                                                                            H  H       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               0  H  H   -- --        H  Cl   Cl H       CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-1                                                                               0  H  H   -- --        H  CH.sub.3                                                                            F  H       OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               0  H  CH.sub.3                                                                           -- --        H  H    H  H       Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               0  CH.sub.3                                                                          H      --        H  H    H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-1                                                                               1  H  H      --        F  F    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-1                                                                               1  H  H      --        H  H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               0  H  H      --        Cl H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-2                                                                               0  H  H      --        F  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               0  H  H      --        H  Br   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               0  H  H      --        F  F    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-2                                                                               0  H  H      --        Cl Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-2                                                                               0  H  H      --        H  F    -- --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4                                                                               Q-2                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  CH.sub.3                                                                           CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               1  H  H      --        H  Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-2                                                                               1  H  H      --        Cl Cl   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-2                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  H   Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  F  F    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Br   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  CH.sub.3                                                                          H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  OCH.sub.3                                                                           -- --  H   Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  F    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Br   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl CH.sub.3                                                                            -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  H  CH.sub.3                                                                              CH.sub.3  H  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               0  CH.sub.3                                                                          H      CH.sub.3  H  H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-3                                                                               1  H  H      CH.sub.3  F  F    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-3                                                                               1  H  H      CH.sub.3  H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-4                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-4                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-4                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4                                                                               Q-4                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-4                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-4                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-5                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  H  H      --        F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-5                                                                               0  H  H      --        H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-5                                                                               0  H  H      --        CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-5                                                                               0  H  H      --        H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  H  H      --        H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  H  H      --        Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  H  H      --        Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-5                                                                               0  H  H      --        F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-5                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  H  CH.sub.3                                                                              --        H  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               0  CH.sub.3                                                                          H      --        H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-5                                                                               1  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-5                                                                               1  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-6                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-6                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               0  H  H      --        H  CH.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-6                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4                                                                               Q-6                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-6                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-6                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-7                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  H  H      --        F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-7                                                                               0  H  H      --        H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-7                                                                               0  H  H      --        CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-7                                                                               0  H  H      --        H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  H  H      --        H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  H  H      --        Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  H  H      --        Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-7                                                                               0  H  H      --        F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-7                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  H  CH.sub.3                                                                              --        H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               0  CH.sub.3                                                                          H      --        H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-7                                                                               1  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-7                                                                               1  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-8                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-8                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               0  H  H      --        H  CH.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-8                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4                                                                               Q-8                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-8                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-8                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  H  CH.sub.3                                                                              CH.sub.3  H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               0  CH.sub.3                                                                          H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-9                                                                               1  H  H      CH.sub.3  F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-9                                                                               1  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              0  H  OCH.sub.3                                                                             CH.sub.3  H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4                                                                               Q-10                                                                              0  CH.sub.3                                                                          Cl     CH.sub.3  F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              1  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4                                                                               Q-10                                                                              1  H  H      CH.sub.3  Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4                                                                               Q-10                                                                              1  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  H  H      --        H  H    H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-1                                                                               0  H  H      --        H  Cl   H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  H  H      --        Cl Cl   H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  H  H      --        F  F    H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-1                                                                               0  H  H      --        H  Br   H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-1                                                                               0  H  H      --        CH.sub.3                                                                          H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-1                                                                               0  H  H      --        H  OCH.sub.3                                                                           H  H   --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  H  H      --        H  F    H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  H  H      --        Cl Br   H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  H  H      --        Cl CH.sub.3                                                                            H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-1                                                                               0  H  H      --        F  CH.sub.3                                                                            H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  H  H      --        H  Cl   Cl H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-1                                                                               0  H  H      --        H  CH.sub.3                                                                            F  F   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  H  CH.sub.3                                                                              --        H  H    H  H   --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               0  CH.sub.3                                                                          H      --        H  H    H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-1                                                                               1  H  H      --        F  F    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-1                                                                               1  H  H      --        H  H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               0  H  H      --        Cl H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-2                                                                               0  H  H      --        F  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               0  H  H      --        H  Br   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               0  H  H      --        F  F    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-2                                                                               0  H  H      --        Cl Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub. 3                                                                           -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-2                                                                               0  H  H      --        H  F    -- --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5                                                                               Q-2                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  CH.sub.3                                                                           CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               1  H  H      --        H  Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-2                                                                               1  H  H      --        Cl Cl   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-2                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  H   Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  F  F    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Br   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  CH.sub.3                                                                          H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  OCH.sub.3                                                                           -- --  H   Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  F    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Br   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl CH.sub.3                                                                            -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Cl   -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  H  CH.sub.3                                                                              CH.sub.3  H  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               0  CH.sub.3                                                                          H      CH.sub.3  H  H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-3                                                                               1  H  H      CH.sub.3  F  F    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-3                                                                               1  H  H      CH.sub.3  H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-4                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-4                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-4                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5                                                                               Q-4                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-4                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-4                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-5                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               0  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               0  H  H      --        F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-5                                                                               0  H  H      --        H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-5                                                                               0  H  H      --        CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-5                                                                               0  H  H      --        H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               0  H  H      --        Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               0  H  H      --        Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-5                                                                               0  H  H      --        F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-5                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               0  H  CH.sub.3                                                                              --        H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               0  CH.sub.3                                                                          H      --        H  H    -- --  --  CH.sub.3                                                                           OCH.sub.                                                                           N                      L-5                                                                               Q-5                                                                               1  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-5                                                                               1  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-6                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-6                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-6                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5                                                                               Q-6                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-6                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-6                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-7                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  H  H      --        F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-7                                                                               0  H  H      --        H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-7                                                                               0  H  H      --        CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-7                                                                               0  H  H      --        H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  H  H      --        H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  H  H      --        Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  H  H      --        Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-7                                                                               0  H  H      --        F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-7                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  H  CH.sub.3                                                                              --        H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               0  CH.sub.3                                                                          H      --        H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-7                                                                               1  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-7                                                                               1  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-8                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-8                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-8                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5                                                                               Q-8                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5                                                                               Q-8                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-8                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-8                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  H  CH.sub.3                                                                              CH.sub.3  H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               0  CH.sub.3                                                                          H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-9                                                                               1  H  H      CH.sub.3  F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-9                                                                               1  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-10                                                                              0  H  H      CH.sub.2 CH.sub.3                                                                        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              0  H  OCH.sub.3                                                                             CH.sub.3  H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5                                                                               Q-10                                                                              0  CH.sub.3                                                                          Cl     CH.sub.3  F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              1  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5                                                                               Q-10                                                                              1  H  H      CH.sub.3  Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5                                                                               Q-10                                                                              1  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  H  H      --        H  H    H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-1                                                                               0  H  H      --        H  Cl   H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  H  H      --        Cl Cl   H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  H  H      --        F  F    H  H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-1                                                                               0  H  H      --        H  Br   H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-1                                                                               0  H  H      --        CH.sub.3                                                                          H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-1                                                                               0  H  H      --        H  OCH.sub.3                                                                           H  H   --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  H  H      --        H  F    H  H   --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  H  H      --        Cl Br   H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  H  H      --        Cl CH.sub.3                                                                            H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-1                                                                               0  H  H      --        F  CH.sub.3                                                                            H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  H  H      --        H  Cl   Cl H   --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-1                                                                               0  H  H      --        H  CH.sub.3                                                                            F  F   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  H  CH.sub.3                                                                              --        H  H    H  H   --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               0  CH.sub.3                                                                          H      --        H  H    H  H   --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               0-1                                                                               1  H  H      --        F  F    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-1                                                                               1  H  H      --        H  H    H  H   --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-6                                                                               Q-2                                                                               0  H  H      --        H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               0  H  H      --        Cl H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-2                                                                               0  H  H      --        F  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               0  H  H      --        H  Br   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               0  H  H      --        F  F    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-2                                                                               0  H  H      --        Cl Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-2                                                                               0  H  H      --        H  F    -- --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  H   OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6                                                                               Q-2                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  CH.sub.3                                                                           CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               1  H  H      --        H  Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-2                                                                               1  H  H      --        Cl Cl   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-2                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  H   Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  H    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Cl   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  H  H      CH.sub. 3 F  F    -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Br   -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  CH.sub.3                                                                          H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  OCH.sub.3                                                                           -- --  H   Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  F    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl Br   -- --  CH.sub.3                                                                           OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  Cl CH.sub.3                                                                            -- --  CH.sub.3                                                                           CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  Cl   -- --  H   CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-3                                                                               0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  H  CH.sub.3                                                                              CH.sub.3  H  H    -- --  H   Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               0  CH.sub.3                                                                          H      CH.sub.3  H  H    -- --  H   CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-3                                                                               1  H  H      CH.sub.3  F  F    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-3                                                                               1  H  H      CH.sub.3  H  H    -- --  H   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-6                                                                               Q-4                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-4                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-4                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-4                                                                               0  H  H      --        H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6                                                                               Q-4                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-4                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-4                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-5                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  H  H      --        F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-5                                                                               0  H  H      --        H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-5                                                                               0  H  H      --        CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-5                                                                               0  H  H      --        H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  H  H      --        H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  H  H      --        Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  H  H      --        Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-5                                                                               0  H  H      --        F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-5                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  H  CH.sub.3                                                                              --        H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               0  CH.sub.3                                                                          H      --        H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-5                                                                               1  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-5                                                                               1  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-6                                                                               Q-6                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-6                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-6                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-6                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6                                                                               Q-6                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-6                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-6                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-7                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  H  H      --        F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-7                                                                               0  H  H      --        H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-7                                                                               0  H  H      --        CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-7                                                                               0  H  H      --        H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  H  H      --        H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  H  H      --        Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  H  H      --        Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-7                                                                               0  H  H      --        F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-7                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  H  CH.sub.3                                                                              --        H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               0  CH.sub.3                                                                          H      --        H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-7                                                                               1  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-7                                                                               1  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-6                                                                               Q-8                                                                               0  H  H      --        H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               0  H  H      --        Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-8                                                                               0  H  H      --        F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               0  H  H      --        H  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               0  H  H      --        F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-8                                                                               0  H  H      --        Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               0  H  H      --        H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               0  H  H      --        CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               0  H  H      --        H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-8                                                                               0  H  H      --        H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               0  H  OCH.sub.3                                                                             --        H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6                                                                               Q-8                                                                               0  CH.sub.3                                                                          Cl     --        F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               1  H  H      --        H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-8                                                                               1  H  H      --        Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-8                                                                               1  H  H      --        F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  F  F    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Br   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  CH.sub.3                                                                          H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  OCH.sub.3                                                                           -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  F    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  H  H      CH.sub.2 CH.sub.3                                                                        Cl Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  H  H      CH.sub.2 CH.sub.3                                                                        Cl CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6                                                                               Q-9                                                                               0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  H  CH.sub.3                                                                              CH.sub.3  H  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               0  CH.sub.3                                                                          OCH.sub.3                                                                             CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-9                                                                               1  H  H      CH.sub.3  F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-9                                                                               1  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  H    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  Cl H    -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  H    -- --  --  Cl  OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  Br   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  F  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  Cl Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  CH.sub.3                                                                          CH.sub.3                                                                            -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  CO.sub.2 CH.sub.3                                                                   -- --  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6                                                                               Q-10                                                                              0  H  H      CH.sub.3  H  F    -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  H  OCH.sub.3                                                                             CH.sub.3  H  Cl   -- --  --  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6                                                                               Q-10                                                                              0  CH Cl     CH.sub.3  F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              0  CH.sub.3                                                                          Cl     CH.sub.3  F  CH.sub.3                                                                            -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              1  H  H      CH.sub.3  H  Cl   -- --  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6                                                                               Q-10                                                                              1  H  H      CH.sub.3  Cl Cl   -- --  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6                                                                               Q-10                                                                              1  H  H      CH.sub.3  F  CH.sub.3                                                                            -- --  --  Cl  OCH.sub.3                                                                          CH                     __________________________________________________________________________

                                      TABLE IIA                                    __________________________________________________________________________     General Structure II (wherein R.sub.12 is OH and R.sub.13 is H)                                                            m.P.                               L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                          R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)                       __________________________________________________________________________     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  F    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  CH.sub.3                                                                           --                                                                               H  H    H H  -- Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 CH.sub.3                                                                          H   --                                                                               H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  H    H H  -- OCH.sub.3                                                                          OCH.sub. 3                                                                         CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-2                                                                               1 H  H   --                                                                               F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                     L-2                                                                               Q-2                                                                               1 H  H   --                                                                               Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  OCH.sub.3                                                                          --                                                                               H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                     L-2                                                                               Q-2                                                                               1 CH.sub.3                                                                          Cl  --                                                                               F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    __________________________________________________________________________

                                      TABLE IIB                                    __________________________________________________________________________     General Structure II (wherein R.sub.12 is OCH.sub.3 and R.sub.13 is H)                                                     m.p.                               L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                          R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)                       __________________________________________________________________________     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub. 3                                                                         N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  F    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  CH.sub.3                                                                           --                                                                               H  H    H H  -- Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 CH.sub.3                                                                          H   --                                                                               H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  H    H H  -- OCH.sub. 3                                                                         OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-2                                                                               1 H  H   --                                                                               F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                     L-2                                                                               Q-2                                                                               1 H  H   --                                                                               Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  OCH.sub.3                                                                          --                                                                               H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                     L-2                                                                               Q-2                                                                               1 CH.sub.3                                                                          Cl  --                                                                               F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    __________________________________________________________________________

                                      TABLE IIC                                    __________________________________________________________________________      General Structure II (wherein R.sub.12 is OH and R.sub.13 is                  __________________________________________________________________________     H)                                                                                                                            m.p.                            L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                             R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)                    __________________________________________________________________________     L-2                                                                               Q-4                                                                               1 H  H   --   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-2                                                                               Q-4                                                                               1 H  H   --   H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               1 H  H   --   CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               1 H  H   --   H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               1 H  H   --   F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-2                                                                               Q-4                                                                               1 H  H   --   H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  CH.sub.3                                                                           --   H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 CH.sub.3                                                                          H   --   H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               1 H  H   --   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               1 H  H   --   F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               1 H  H   --   Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   CH.sub. 3                                                                         CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-4                                                                               1 H  H   --   H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  OCH.sub.3                                                                          --   H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                  L-2                                                                               Q-4                                                                               1 CH.sub.3                                                                          Cl  --   F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 __________________________________________________________________________                                                    m.p.                            L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.3                                                                             R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)                    __________________________________________________________________________     L-4                                                                               Q-1                                                                               1 CH.sub.3                                                                          H   --   H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-4                                                                               Q-1                                                                               1 H  H   --   F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-1                                                                               1 H  H   --   H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-4                                                                               Q-2                                                                               1 H  H   --   F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-4                                                                               Q-2                                                                               1 H  H   --   Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  OCH.sub.3                                                                          --   H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                  L-4                                                                               Q-2                                                                               1 CH.sub.3                                                                          Cl  --   F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-4                                                                               Q-2                                                                               1 H  H   --   Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-4                                                                               Q-2                                                                               1 H  H   --   F  CH.sub.3                                                                            --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                                 L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            F  F    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            H  Br   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            CH.sub.3                                                                          H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            H  OCH.sub.3                                                                           --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                                 L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            H  F    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            Cl Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            Cl CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            F  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-4                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                            Cl Cl   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                                 L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-5                                                                               Q-10                                                                              1 H  H   CH.sub. 3                                                                           F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-5                                                                               Q-10                                                                              1 H  H   CH.sub.2 CH.sub.3                                                                   Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-5                                                                               Q-10                                                                              1 H  OCH.sub.3                                                                          CH.sub.3                                                                            H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                                  L-5                                                                               Q-10                                                                              1 CH.sub.3                                                                          Cl  CH.sub.3                                                                            F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            Cl Cl   --                                                                               -- -- OCH.sub. 3                                                                         OCH.sub.3                                                                          N                                  L-5                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                            F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-6                                                                               Q-1                                                                               1 H  H   --   H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-6                                                                               Q-1                                                                               1 H  H   --   CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-6                                                                               Q-1                                                                               1 H  H   --   H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   H  F    H H  -- CH.sub.3                                                                           Cl  CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-6                                                                               Q-1                                                                               1 H  H   --   F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-6                                                                               Q-1                                                                               1 H  H   --   H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 H  CH.sub.3                                                                           --   H  H    H H  -- Cl  OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 CH.sub.3                                                                          H   --   H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-6                                                                               Q-1                                                                               1 H  H   --   F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-6                                                                               Q-1                                                                               1 H  H   --   H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-6                                                                               Q-2                                                                               1 H  H   --   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-6                                                                               Q-2                                                                               1 H  H   --   H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 __________________________________________________________________________

                                      TABLE IID                                    __________________________________________________________________________      General Structure IIa (where R.sub.12 and R.sub.13 are                        __________________________________________________________________________     H)                                                                                                                                 m.p.                       L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                             R.sub.10                                                                              R.sub.11                                                                          X   Y   Z  (°C.)               __________________________________________________________________________     L-2                                                                               Q-1                                                                               0 H  H   -- H  H    H    H      -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-1                                                                               0 H  H   -- H  Cl   H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               0 H  H   -- Cl Cl   H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               0 H  H   -- F  F    H    H      -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-2                                                                               Q-1                                                                               0 H  H   -- H  Br   H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-1                                                                               0 H  H   -- CH.sub.3                                                                          H    H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-2                                                                               Q-1                                                                               0 H  H   -- H  OCH.sub.3                                                                           H    H      -- Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               0 H  H   -- H  F    H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               0 H  H   -- Cl Br   H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               0 H  H   -- Cl CH.sub.3                                                                            H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-1                                                                               0 H  H   -- F  CH.sub.3                                                                            H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               0 H  H   -- H  Cl   Cl   H      -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-2                                                                               Q-1                                                                               0 H  H   -- H  CH.sub.3                                                                            F    F      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               0 H  CH.sub.3                                                                           -- H  H    H    H      -- Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               0 CH.sub.3                                                                          H   -- H  H    H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-1                                                                               1 H  H   -- F  F    H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-1                                                                               1 H  H   -- H  H    H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               0 H  H   -- H  H    --   --     H  CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-2                                                                               0 H  H   -- H  H    --   --     H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                            L-2                                                                               Q-2                                                                               0 H  H   -- H  H    --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               0 H  H   -- Cl H    --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-2                                                                               0 H  H   -- F  H    --   --     H  Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               0 H  H   -- H  Br   --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               0 H  H   -- F  F    --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-2                                                                               Q-2                                                                               0 H  H   -- Cl Cl   --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               0 H  H   -- H  CH.sub.3                                                                            --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               0 H  H   -- CH.sub.3                                                                          CH.sub.3                                                                            --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               0 H  H   -- H  CO.sub.2 CH.sub.3                                                                   --   --     H  CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-2                                                                               0 H  H   -- H  F    --   --     CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               0 H  OCH.sub.3                                                                          -- H  Cl   --   --     H  OCH.sub.3                                                                          CH.sub.3                                                                           N                             L-2                                                                               Q-2                                                                               0 CH.sub.3                                                                          Cl  -- F  CH.sub.3                                                                            --   --     CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                            __________________________________________________________________________                                                         m.p.                       L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.3                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                             R.sub.10                                                                              R.sub.11                                                                          X   Y   Z  (°C.)               __________________________________________________________________________     L-2                                                                               Q-2                                                                               1 H  H   -- H  Cl   --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-2                                                                               1 H  H   -- Cl Cl   --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-2                                                                               Q-2                                                                               1 H  H   -- F  CH.sub.3                                                                            --   --     H  Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     H  CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          F  F    --   --     H  CH.sub.3                                                                           CH.sub.3                                                                           N                             L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Br   --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          H    --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  OCH.sub.3                                                                           --   --     H  Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  F    --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl Br   --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl CH.sub.3                                                                            --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --   --     CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --   --     H  CH.sub.3                                                                           CH.sub.3                                                                           N                             L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          H  H    --   --     H  Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          H  H    --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                          F  F    --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                          H  H    --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-4                                                                               0 H  H   -- H  H    --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-4                                                                               0 H  H   -- H  H    --   --     -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                            L-2                                                                               Q-4                                                                               0 H  H   -- H  H    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-4                                                                               0 H  H   -- Cl H    --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-4                                                                               0 H  H   -- F  H    --   --     -- Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-4                                                                               0 H  H   -- H  Br   --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-4                                                                               0 H  H   -- F  F    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-2                                                                               Q-4                                                                               0 H  H   -- Cl Cl   --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-4                                                                               0 H  H   -- H  CH.sub.3                                                                            --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-4                                                                               0 H  H   -- CH.sub.3                                                                          CH.sub.3                                                                            --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-4                                                                               0 H  H   -- H  CO.sub.2 CH.sub.3                                                                   --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-4                                                                               0 H  H   -- H  F    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-4                                                                               0 H  OCH.sub.3                                                                          -- H  Cl   --   --     -- OCH.sub.3                                                                          CH.sub.3                                                                           N                             L-2                                                                               Q-8                                                                               0 H  H   -- H  CO.sub.2 CH.sub.3                                                                   --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-8                                                                               0 H  H   -- H  F    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-8                                                                               0 H  OCH.sub.3                                                                          -- H  Cl   --   --     -- OCH.sub.3                                                                          CH.sub.3                                                                           N                             L-2                                                                               Q-8                                                                               0 CH.sub.3                                                                          Cl  -- F  CH.sub.3                                                                            --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-8                                                                               1 H  H   -- H  Cl   --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-8                                                                               1 H  H   -- Cl Cl   --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-2                                                                               Q-8                                                                               1 H  H   -- F  CH.sub.3                                                                            --   --     -- Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          F  F    --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  Br   --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          H    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  OCH.sub.3                                                                           --   --     -- Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  F    --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          Cl Br   --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          Cl CH.sub.3                                                                            --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-2                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          H  H    --   --     -- Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          H  H    --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-9                                                                               1 H  H   CH.sub.3                                                                          F  F    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-9                                                                               1 H  H   CH.sub.3                                                                          H  H    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  H    --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-2                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  H    --   --     -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                            L-2                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  H    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          Cl H    --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-2                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          F  H    --   --     -- Cl  OCH.sub.3                                                                          CH                            L-2                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  Br   --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-2                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          F  F    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-2                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          Cl Cl   --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            __________________________________________________________________________                                                         m.p.                       L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                             R.sub.10                                                                              R.sub.11                                                                          X   Y   Z  (°                  __________________________________________________________________________                                                         C.)                        L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  H    H    H      -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  Cl   H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          F  F    H    H      -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  Br   H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          H    H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  OCH.sub.3                                                                           H    H      -- Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  F    H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          Cl Br   H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          Cl CH.sub.3                                                                            H    H      -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            H    H      -- OCH.sub.3                                                                          OCH.sub. 3                                                                         CH                            L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  Cl   Cl   H      -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            F    F      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-1                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          H  H    H    H      -- Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-1                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          H  H    H    H      -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-1                                                                               1 H  H   CH.sub.3                                                                          F  F    H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-1                                                                               1 H  H   CH.sub.3                                                                          H  H    H    H      -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     H  CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          Cl H    --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          F  H    --   --     H  Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  Br   --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            __________________________________________________________________________                                                         m.p.                       L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.3                                                                             R.sub.10                                                                              R.sub.11                                                                          X   Y   Z  (°C.)               __________________________________________________________________________     L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          F  F    --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3                                                                            --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  CO.sub.2 CH.sub.3                                                                   --   --     H  CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  F    --   --     CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               0 H  OCH.sub.3                                                                          CH.sub.3                                                                          H  Cl   --   --     H  OCH.sub. 3                                                                         CH.sub.3                                                                           N                             L-3                                                                               Q-2                                                                               0 CH.sub.3                                                                          Cl  CH.sub.3                                                                          F  CH.sub.3                                                                            --   --     CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               1 H  H   CH.sub.3                                                                          H  Cl   --   --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-2                                                                               1 H  H   CH.sub.3                                                                          Cl Cl   --   --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-3                                                                               Q-2                                                                               1 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --   --     H  Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  H    CH.sub.3                                                                            --     H  CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Cl   CH.sub.3                                                                            --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   CH.sub.3                                                                            --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          F  F    CH.sub.3                                                                            --     H  CH.sub.3                                                                           CH.sub.3                                                                           N                             L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Br   CH.sub.3                                                                            --     H  CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          H    CH.sub.3                                                                            --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  OCH.sub.3                                                                           CH.sub.3                                                                            --     H  Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  F    CH.sub.3                                                                            --     H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl Br   CH.sub.3                                                                            --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl CH.sub.3                                                                            CH.sub.3                                                                            --     H  CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            CH.sub.3                                                                            --     CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Cl   CH.sub.2 CH.sub.3                                                                   --     H  CH.sub.3                                                                           CH.sub.3                                                                           N                             L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            CH.sub.3                                                                            --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          H  H    CH.sub.3                                                                            --     H  Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          H  H    CH.sub.3                                                                            --     H  CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                          F  F    CH.sub.3                                                                            --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                          H  H    CH.sub.3                                                                            --     H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                            L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          Cl H    --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             __________________________________________________________________________                                                         m.p.                       L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                             R.sub.3                                                                               R.sub.11                                                                          X   Y   Z  (°C.)               __________________________________________________________________________     L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          H  H    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          Cl H    --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          F  H    --   --     -- Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          H  Br   --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          F  F    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3                                                                            --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                   --   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          H  F    --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               0 H  OCH.sub.3                                                                          CH.sub.3                                                                          H  Cl   --   --     -- OCH.sub.3                                                                          CH.sub.3                                                                           N                             L-3                                                                               Q-8                                                                               0 CH.sub.3                                                                          Cl  CH.sub.3                                                                          F  CH.sub.3                                                                            --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               1 H  H   CH.sub.3                                                                          H  Cl   --   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-8                                                                               1 H  H   CH.sub.3                                                                          Cl Cl   --   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-3                                                                               Q-8                                                                               1 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --   --     -- Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  H    --   CH.sub.3                                                                              -- CH.sub.3                                                                           CH.sub.3                                                                           CH                            L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --   CH.sub.3                                                                              -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   --   CH.sub.3                                                                              -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          F  F    --   CH.sub.3                                                                              -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  Br   --   CH.sub.3                                                                              -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          H    --   CH.sub.3                                                                              -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                             L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  OCH.sub.3                                                                           --   CH.sub.3                                                                              -- Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  F    --   CH.sub.3                                                                              -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          Cl Br   --   CH.sub.3                                                                              -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          Cl CH.sub.3                                                                            --   CH.sub.3                                                                              -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --   CH.sub.3                                                                              -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --   CH.sub.3                                                                              -- CH.sub.3                                                                           CH.sub.3                                                                           N                             L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --   CH.sub.2 CH.sub.3                                                                     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          H  H    --   CH.sub.2 CH.sub.3                                                                     -- Cl  OCH.sub.3                                                                          CH                            L-3                                                                               Q-9                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          H  H    --   CH.sub.2 CH.sub.2 CH.sub.3                                                            -- CH.sub.3                                                                           OCH.sub.3                                                                          N                             __________________________________________________________________________

                                      TABLE IIE                                    __________________________________________________________________________      General Structure IIb (wherein R.sub.12 and R.sub.13 are                      __________________________________________________________________________     H)                                                                                                                            m.p.                            L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                            R.sub.11                                                                          X   Y   Z  (°C.)                    __________________________________________________________________________     L-2                                                                               Q-1                                                                               0 H  H   -- H  H    H H    -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- H  Cl   H H    -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- Cl Cl   H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- F  F    H H    -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-2                                                                               Q-1                                                                               0 H  H   -- H  Br   H H    -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-1                                                                               0 H  H   -- CH.sub.3                                                                          H    H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-1                                                                               0 H  H   -- H  OCH.sub.3                                                                           H H    -- Cl  OCH.sub. 3                                                                         CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- H  F    H H    -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- Cl Br   H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- Cl CH.sub.3                                                                            H H    -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-1                                                                               0 H  H   -- F  CH.sub.3                                                                            H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- H  Cl   Cl                                                                               H    -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-2                                                                               Q-1                                                                               0 H  H   -- H  CH.sub.3                                                                            F F    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  CH.sub.3                                                                           -- H  H    H H    -- Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 CH.sub.3                                                                          H   -- H  H    H H    -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-1                                                                               1 H  H   -- F  F    H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               1 H  H   -- H  H    H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- H  H    --                                                                               --   H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- H  H    --                                                                               --   H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- H  H    --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- Cl H    --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-2                                                                               0 H  H   -- F  H    --                                                                               --   H  Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- H  Br   --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- F  F    --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-2                                                                               0 H  H   -- Cl Cl   --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- H  CH.sub.3                                                                            --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- H  CO.sub.2 CH.sub.3                                                                   --                                                                               --   H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-2                                                                               0 H  H   -- H  F    --                                                                               --   CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               0 H  OCH.sub.3                                                                          -- H  Cl   --                                                                               --   H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                  L-2                                                                               Q-2                                                                               0 CH.sub.3                                                                          Cl  -- F  CH.sub.3                                                                            --                                                                               --   CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- H  OH   --                                                                               H    -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 __________________________________________________________________________                                                    m.p.                            L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.3                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                            R.sub.11                                                                          X   Y   Z  (°C.)                    __________________________________________________________________________     L-2                                                                               Q-1                                                                               0 H  H   -- H  OH   --                                                                               H    -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- H  OH   --                                                                               H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-1                                                                               0 H  H   -- H  OH   --                                                                               H    -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-1                                                                               0 H  H   -- H  OH   --                                                                               H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-1                                                                               0 H  H   -- H  OH   --                                                                               H    -- Cl  OCH.sub.3                                                                          N                                  L-2                                                                               Q-2                                                                               1 H  H   -- H  Cl   --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-2                                                                               1 H  H   -- Cl Cl   --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-2                                                                               1 H  H   -- F  CH.sub.3                                                                            --                                                                               --   H  Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  H    --                                                                               --   H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          F  F    --                                                                               --   H  CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Br   --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          H    --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  OCH.sub.3                                                                           --                                                                               --   H  Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  F    --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl Br   --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          Cl CH.sub.3                                                                            --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --                                                                               --   CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --                                                                               --   H  CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-2                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          H  H    --                                                                               --   H  Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          H  H    --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                          F  F    --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                          H  H    --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- H  H    --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- H  H    --                                                                               --   -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- H  H    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- Cl H    --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               0 H  H   -- F  H    --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- H  Br   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- F  F    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               0 H  H   -- Cl Cl   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 __________________________________________________________________________                                                    m.p.                            L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                            R.sub.11                                                                          X   Y   Z  (°C.)                    __________________________________________________________________________     L-2                                                                               Q-4                                                                               0 H  H   -- H  CH.sub.3                                                                            --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- H  CO.sub.2 CH.sub.3                                                                   --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-4                                                                               0 H  H   -- H  F    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               0 H  OCH.sub.3                                                                          -- H  Cl   --                                                                               --   -- OCH.sub.3                                                                          CH.sub.3                                                                           N                                  L-2                                                                               Q-4                                                                               0 CH.sub.3                                                                          Cl  -- F  CH.sub.3                                                                            --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   -- H  Cl   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-4                                                                               1 H  H   -- Cl Cl   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-4                                                                               1 H  H   -- F  CH.sub.3                                                                            --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 H  H   -- H  H    --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-5                                                                               0 H  H   -- H  Cl   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 H  H   -- Cl Cl   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 H  H   -- F  F    --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-2                                                                               Q-5                                                                               0 H  H   -- H  Br   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-5                                                                               0 H  H   -- CH.sub.3                                                                          H    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-5                                                                               0 H  H   -- H  OCH.sub.3                                                                           --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 H  H   -- H  F    --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 H  H   -- Cl Br   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 H  H   -- Cl CH.sub.3                                                                            --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-5                                                                               0 H  H   -- F  CH.sub.3                                                                            --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 H  H   -- H  Cl   --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-2                                                                               Q-5                                                                               0 H  H   -- H  CH.sub.3                                                                            --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 H  CH.sub.3                                                                           -- H  H    --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               0 CH.sub.3                                                                          H   -- H  H    --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-5                                                                               1 H  H   -- F  F    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-5                                                                               1 H  H   -- H  H    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- H  H    --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- H  H    --                                                                               --   -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- H  H    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- Cl H    --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-2                                                                               Q-6                                                                               0 H  H   -- F  H    --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- H  Br   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- F  F    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-2                                                                               Q-6                                                                               0 H  H   -- Cl Cl   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- H  CH.sub.3                                                                            --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- H  CO.sub.2 CH.sub.3                                                                   --                                                                               --   -- Cl  CH.sub.3                                                                           CH                                 L-2                                                                               Q-6                                                                               0 H  H   -- H  F    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  H    H H    -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  Cl   H H    -- CH.sub. 3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          F  F    H H    -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  Br   H H    -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          H    H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  OCH.sub.3                                                                           H H    -- Cl  OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  F    H H    -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          Cl Br   H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          Cl CH.sub.3                                                                            H H    -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  Cl   Cl                                                                               H    -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            F F    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          H  H    H H    -- Cl  OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          H  H    H H    -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-3                                                                               Q-1                                                                               1 H  H   CH.sub.3                                                                          F  F    H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-1                                                                               1 H  H   CH.sub.3                                                                          H  H    H H    -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  H    --                                                                               --   H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  H    --                                                                               --   H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  H    --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          Cl H    --                                                                               --   H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          F  H    --                                                                               --   H  Cl  OCH.sub.3                                                                          CH                                 L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          H  Br   --                                                                               --   H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          F  H    --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          H  Br   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          F  F    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          H  CO.sub.2 CH.sub.3                                                                   --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          H  F    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               0 H  OCH.sub.3                                                                          CH.sub.3                                                                          H  Cl   --                                                                               --   -- OCH.sub.3                                                                          CH.sub.3                                                                           N                                  L-3                                                                               Q-4                                                                               0 CH.sub.3                                                                          Cl  CH.sub.3                                                                          F  CH.sub.3                                                                            --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               1 H  H   CH.sub.3                                                                          H  Cl   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-4                                                                               1 H  H   CH.sub.3                                                                          Cl Cl   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-3                                                                               Q-4                                                                               1 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          H  H    --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          Cl Cl   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          F  F    --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          H  Br   --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          H    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          H  OCH.sub.3                                                                           --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          H  F    --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          Cl Br   --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          Cl CH.sub.3                                                                            --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          H  Cl   --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           N                                  L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          H  H    --                                                                               --   -- Cl  OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          H  H    --                                                                               --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-3                                                                               Q-5                                                                               1 H  H   CH.sub.3                                                                          F  F    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-5                                                                               1 H  H   CH.sub.3                                                                          H  H    --                                                                               --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-6                                                                               0 H  H   CH.sub.3                                                                          H  H    --                                                                               --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-3                                                                               Q-6                                                                               0 H  H   CH.sub.3                                                                          H  H    --                                                                               --   -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 __________________________________________________________________________                                                    m.p.                            L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.3                                                                             R.sub.10                                                                          X   Y   Z  (°C.)                    __________________________________________________________________________     L-3                                                                               Q-9                                                                               1 H  H   CH.sub.3                                                                          F  F    --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-9                                                                               1 H  H   CH.sub.3                                                                          H  H    --                                                                               CH.sub.2 CH.sub.3                                                                   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  H    --                                                                               CH.sub.3                                                                            -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  H    --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  H    --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          Cl H    --                                                                               CH.sub.3                                                                            -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                  L-3                                                                               Q-10                                                                              0 H  H   CH.sub. 3                                                                         F  H    --                                                                               CH.sub.3                                                                            -- Cl  OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  Br   --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          F  F    --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          Cl Cl   --                                                                               CH.sub.3                                                                            -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  CH.sub.3                                                                            --                                                                               CH.sub.3                                                                            -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  CO.sub.2 CH.sub.3                                                                   --                                                                               CH.sub.3                                                                            -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                 L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          H  F    --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              0 H  OCH.sub.3                                                                          CH.sub.3                                                                          H  Cl   --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          CH.sub.3                                                                           N                                  L-3                                                                               Q-10                                                                              0 CH.sub.3                                                                          Cl  CH.sub.3                                                                          F  CH.sub.3                                                                            --                                                                               CH.sub.3                                                                            -- CH.sub.3                                                                           OCH.sub. 3                                                                         CH                                 L-3                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                          H  Cl   --                                                                               CH.sub.2 CH.sub.3                                                                   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 L-3                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                          Cl Cl   --                                                                               CH.sub.3                                                                            -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  L-3                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                          F  CH.sub.3                                                                            --                                                                               CH.sub.2 CH.sub.3                                                                   -- Cl  OCH.sub.3                                                                          CH                                 __________________________________________________________________________

                                      TABLE III                                    __________________________________________________________________________     General Structure III (wherein R.sub.12 and R.sub.13 are                       __________________________________________________________________________     H)                                                                                                                                  m.p.                      A  Q  n R R.sub.1                                                                          R.sub.3                                                                           R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                           R.sub.10                                                                          R.sub.11                                                                          X.sub.1                                                                             Y.sub.1                                                                           Y.sub.2                                                                           X.sub.2                                                                            Y.sub.3                                                                             X.sub.3                                                                           (°C.)              __________________________________________________________________________     A-2                                                                               Q-1                                                                               0 H H -- H  H  H  H  -- CH.sub.3                                                                            O  -- --  --   --                           A-2                                                                               Q-1                                                                               0 H H -- H  H  H  H  -- CH.sub.3                                                                            CH.sub.2                                                                          -- --  --   --                           A-2                                                                               Q-1                                                                               0 H H -- H  H  H  H  -- OCH.sub.3                                                                           O  -- --  --   --                           A-2                                                                               Q-5                                                                               0 H H -- H  H  -- -- -- CH.sub.3                                                                            CH.sub.2                                                                          -- --  --   --                           A-2                                                                               Q-2                                                                               0 H H -- H  Cl -- -- H  OCF.sub.2 H                                                                         O  -- --  --   --                           A-3                                                                               Q-1                                                                               0 H H -- H  H  H  H  -- CH.sub.3                                                                            -- -- --  --   --                           A-3                                                                               Q-1                                                                               0 H H -- H  H  H  H  -- OCH.sub.3                                                                           -- -- --  --   --                           A-3                                                                               Q-1                                                                               0 H H -- H  F  H  Cl -- OCF.sub.2 H                                                                         -- -- --  --   --                           A-3                                                                               Q-1                                                                               1 H H -- Cl Cl H  H  -- CH.sub.3                                                                            -- -- --  --   --                           A-3                                                                               Q-1                                                                               0 H H -- CH.sub.3                                                                          H  H  H  -- OCH.sub.3                                                                           -- -- --  --   --                           A-3                                                                               Q-4                                                                               0 H H -- H  H  -- -- -- OCH.sub.3                                                                           -- -- --  --   --                           A-3                                                                               Q-3                                                                               0 H H CH.sub.3                                                                          H  CH.sub.3                                                                          -- -- H  CH.sub.3                                                                            -- -- --  --   --                           A-4                                                                               Q-1                                                                               0 H H -- H  H  H  H  -- CH.sub.3                                                                            -- H  --  --   --                           A-4                                                                               Q-1                                                                               0 H H -- H  Cl H  H  -- OCH.sub.3                                                                           -- H  --  --   --                           A-4                                                                               Q-1                                                                               1 H H -- F  F  Cl CH.sub.3                                                                          -- CH.sub.3                                                                            -- CH.sub.3                                                                          --  --   --                           A-4                                                                               Q-6                                                                               0 H H -- H  H  -- -- -- OCH.sub.3                                                                           -- H  --  --   --                           A-4                                                                               Q-7                                                                               0 H H -- CH.sub.3                                                                          F  -- -- -- CH.sub.3                                                                            -- CH.sub.3                                                                          --  --   --                           A-5                                                                               Q-1                                                                               0 H H -- H  H  H  H  -- --   -- -- CH.sub.3                                                                           CH.sub.3                                                                            --                           A-5                                                                               Q-1                                                                               0 H H -- Cl H  H  Cl -- --   -- -- OCH.sub.3                                                                          CH.sub.3                                                                            --                           A-5                                                                               Q-10                                                                              0 H H CH.sub.3                                                                          H  H  -- -- -- --   -- -- CH.sub.3                                                                           CH.sub.2 CF.sub.3                                                                   --                           A-6                                                                               Q-1                                                                               0 H H -- H  H  H  H  -- --   -- -- --  --   CH.sub.3                     __________________________________________________________________________                                                          m.p.                                        A  Q  n R R.sub.1                                                                          R.sub.7                                                                          R.sub.8                                                                          R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X.sub.4                                                                            Y.sub.4                                                                            Z  (°C.)              __________________________________________________________________________                       A-7                                                                               Q-1                                                                               0 H H H H H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                             A-7                                                                               Q-1                                                                               0 H H H H H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                              A-7                                                                               Q-2                                                                               0 H H H H --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                             A-7                                                                               Q-2                                                                               0 H H H H --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                              A-7                                                                               Q-4                                                                               0 H H H H --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                             A-7                                                                               Q-4                                                                               0 H H H H --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                            __________________________________________________________________________

                                      TABLE IV                                     __________________________________________________________________________     General Structure IV                                                                                                                m.p.                      L  Q  A  R.sub.1                                                                          R.sub.2                                                                           R.sub.3                                                                           R.sub.7                                                                          R.sub.8                                                                           R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X.sub.1                                                                              Y.sub.1                                                                           Y.sub.2                                                                           X.sub.2                                                                            Y.sub.3                                                                           X.sub.3                                                                            (°C.)              __________________________________________________________________________     L-2                                                                               Q-1                                                                               A-2                                                                               H -- -- H H  H H  -- CH.sub.3                                                                             O  -- --  -- --                            L-2                                                                               Q-6                                                                               A-4                                                                               H -- -- H Cl --                                                                               -- -- OCH.sub.3                                                                            -- H  --  -- --                            L-2                                                                               Q-10                                                                              A-5                                                                               H -- CH.sub.3                                                                          H H  --                                                                               -- -- --    -- -- OCH.sub.3                                                                          CH.sub.3                                                                          --                            L-3                                                                               Q-1                                                                               A-3                                                                               H CH.sub.3                                                                          -- H H  H H  -- OCH.sub.3                                                                            -- -- --  -- --                            L-3                                                                               Q-1                                                                               A-6                                                                               H CH.sub.3                                                                          -- Cl                                                                               H  H H  -- --    -- -- --  -- OCH.sub.3                     L-3                                                                               Q-3                                                                               A-2                                                                               H CH.sub.3                                                                          CH.sub.3                                                                          H H  --                                                                               -- H  OCH.sub.3                                                                            CH.sub.2                                                                          -- --  -- --                            L-4                                                                               Q-1                                                                               A-3                                                                               H -- -- H H  H H  -- OCH.sub.3                                                                            -- -- --  -- --                            L-4                                                                               Q-1                                                                               A-4                                                                               H -- -- H F  H H  -- OCH.sub.3                                                                            -- CH.sub.3                                                                          --  -- --                            L-4                                                                               Q-2                                                                               A-2                                                                               H -- -- H CH.sub.3                                                                          --                                                                               -- H  OCF.sub.2 H                                                                          O  -- --  -- --                            L-4                                                                               Q-3                                                                               A-4                                                                               H -- CH.sub.3                                                                          H H  --                                                                               -- H  CH.sub.3                                                                             -- CH.sub.3                                                                          --  -- --                            L-5                                                                               Q-1                                                                               A-2                                                                               H -- -- H H  H H  -- OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                                                          -- --  -- --                            L-5                                                                               Q-1                                                                               A-6                                                                               H -- -- H Cl H H  -- --    -- -- --  -- CH.sub.3                      L-5                                                                               Q-4                                                                               A-2                                                                               H -- -- H H  --                                                                               -- -- OCH.sub.3                                                                            O  -- --  -- --                            L-5                                                                               Q-7                                                                               A-5                                                                               H -- -- H H  --                                                                               -- -- --    -- -- SCH.sub.3                                                                          CH.sub.3                                                                          --                            L-6                                                                               Q-1                                                                               A-2                                                                               H -- -- H H  H H  -- CH.sub.3                                                                             O  -- --  -- --                            L-6                                                                               Q-5                                                                               A-2                                                                               H -- -- H CH.sub.3                                                                          --                                                                               -- -- CH.sub.3                                                                             CH.sub.2                                                                          -- --  -- --                            L-6                                                                               Q-8                                                                               A-6                                                                               H -- -- H H  --                                                                               -- -- --    -- -- --  -- OCH.sub.3                     L-6                                                                               Q-9                                                                               A-2                                                                               H -- CH.sub.3                                                                          H H  --                                                                               -- -- OCH.sub.3                                                                            O  -- --  -- --                            L-2                                                                               Q-1                                                                               A-2                                                                               H -- -- H OH --                                                                               -- -- OCH.sub.3                                                                            O  -- --  -- --                            __________________________________________________________________________

                                      TABLE V                                      __________________________________________________________________________     General Structure V (where R.sub.9 and R.sub.10 are a carbonyl group)          L  Q  R  R.sub.1                                                                          R.sub.2                                                                           R.sub.7                                                                          R.sub.8                                                                               X   Y   Z  m.p.(°C.)                             __________________________________________________________________________     L-1                                                                               Q-1                                                                               H  H -- H H      CH.sub.3                                                                           CH.sub.3                                                                           CH                                              L-1                                                                               Q-1                                                                               H  H -- H H      OCH.sub.3                                                                          CH.sub.3                                                                           CH                                              L-1                                                                               Q-1                                                                               H  H -- H H      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              L-1                                                                               Q-1                                                                               H  H -- H H      CH.sub.3                                                                           CH.sub.3                                                                           N                                               L-1                                                                               Q-1                                                                               H  H -- H H      OCH.sub.3                                                                          CH.sub.3                                                                           N                                               L-1                                                                               Q-1                                                                               H  H -- H H      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               L-1                                                                               Q-1                                                                               H  H -- H Cl     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              L-1                                                                               Q-1                                                                               H  H -- H F      CH.sub.3                                                                           OCH.sub.3                                                                          N                                               L-1                                                                               Q-1                                                                               H  H -- H Br     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              L-1                                                                               Q-1                                                                               H  H -- H CN     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              L-1                                                                               Q-1                                                                               H  H -- H CH.sub.3                                                                              CH.sub.3                                                                           OCH.sub. 3                                                                         N                                               L-1                                                                               Q-1                                                                               H  H -- H OCH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                              L-1                                                                               Q-1                                                                               H  H -- H CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               L-1                                                                               Q-1                                                                               H  H -- H SO.sub.2 N(CH.sub.3).sub.2                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              L-1                                                                               Q-1                                                                               H  H -- H SCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              L-1                                                                               Q-1                                                                               H  H -- H SO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           N                                               L-1                                                                               Q-1                                                                               CH.sub.3                                                                          H -- H H      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              L-2                                                                               Q-1                                                                               H  H -- H H      CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              L-2                                                                               Q-1                                                                               H  H -- H H      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               L-3                                                                               Q-1                                                                               H  H CH.sub.3                                                                          H H      OCH.sub.3                                                                          CH.sub.3                                                                           CH                                              L-3                                                                               Q-1                                                                               H  H CH.sub.3                                                                          H H      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              L-4                                                                               Q-1                                                                               H  H -- H H      CH.sub.3                                                                           OCH.sub.3                                                                          N                                               L-4                                                                               Q-1                                                                               H  H -- H CH.sub.3                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                              L-5                                                                               Q-1                                                                               H  H -- H H      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              L-5                                                                               Q-1                                                                               H  H -- H Cl     CH.sub.3                                                                           CH.sub.3                                                                           CH                                              L-6                                                                               Q-1                                                                               H  H -- H H      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                               L-6                                                                               Q-1                                                                               H  H -- H H      CH.sub.3                                                                           CH.sub.3                                                                           N                                               L-6                                                                               Q-1                                                                               H  H -- Cl                                                                               Cl     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                              __________________________________________________________________________

Formulations

Useful formulations of the compounds of Formula I can be prepared in conventional ways. They include dusts, granules, pellets, solutions, suspensions, emulsions, wettable powders, emulsifiable concentrates and the like. Many of these may be applied directly. Sprayable formulations can be extended in suitable media and used at spray volumes of from a few liters to several hundred liters per hectare. High strength compositions are primarily used as intermediates for further formulation. The formulations, broadly, contain about 0.1% to 99% by weight of active ingredient(s) and at least one of (a) about 0.1% to 20% surfactant(s) and (b) about 1% to 99.9% solid or liquid inert diluent(s). More specifically, they will contain these ingredients in the following approximate proportions:

    ______________________________________                                                     Active  Weight Percent*                                                        Ingredient                                                                             Diluent(s)                                                                               Surfactant(s)                                    ______________________________________                                         Wettable Powders                                                                             20-90      0-74     1-10                                         Oil Suspensions,                                                                              3-50     40-95     0-15                                         Emulsions, Solutions,                                                          (including Emulsifiable                                                        Concentrates)                                                                  Aqueous Suspension                                                                           10-50     40-84     1-20                                         Dusts          1-25     70-99     0-5                                          Granules and Pellets                                                                         0.1-95      5-99.9  0-15                                         High Strength 90-99      0-10     0-2                                          Compositions                                                                   ______________________________________                                          *Active ingredient plus at least one of a Surfactant or a Diluent equals       100 weight percent.                                                      

Lower or higher levels of active ingredients can, of course, be present depending on the intended use and the physical properties of the compound. Higher ratios of surfactant to active ingredient are sometimes desirable, and are achieved by incorporation into the formulation or by tank mixing.

Typical solid diluents are described in Watkins, et al., "Handbook of Insecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books, Caldwell, N.J., but other solids, either mined or manufactured, may be used. The more absorptive diluents are preferred for wettable powders and the denser ones for dusts. Typical liquid diluents and solvents are described in Marsden, "Solvents Guide," 2nd Ed., Interscience, New York, 1950. Solubility under 0.1% is preferred for suspension concentrates; solution concentrates are preferably stable against phase separation at 0° C. "McCutcheon's Detergents and Emulsifiers Annual", MC Publishing Corp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia of Surface Active Agents", Chemical Publishing Co., Inc., New York, 1964, list surfactants and recommended uses. All formulations can contain minor amounts of additives to reduce foaming, caking, corrosion, microbiological growth, etc.

The methods of making such compositions are well known. Solutions are prepared by simply mixing the ingredients. Fine solid compositions are made by blending and, usually, grinding as in a hammer or fluid energy mill. Suspensions are prepared by wet milling (see, for example, Littler, U.S. Pat. No. 3,060,084). Granules and pellets may be made by spraying the active material upon preformed granular carriers or by agglomeration techniques. See J. E. Browning, "Agglomeration", Chemical Engineering, Dec. 4, 1967, pp. 147ff. and "Perry's Chemical Engineer's Handbook", 5th Ed., McGraw-Hill, New York, 1973, pp. 8-57ff.

For further information regarding the art of formulation, see for example:

H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16 through Col. 7, line 19 and Examples 10 through 41;

R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line 43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58, 132, 138-140, 162-164, 166, 167 and 169-182;

H. Gysin and E. Knusli, U.S. Pat. No. 2,891,855, June 23, 1959, Col. 3, line 66 through Col. 5, line 17 and Examples 1-4;

G. C. Klingman, "Weed Control as a Science", John Wiley and Sons, Inc., New York, 1961, pp. 81-96; and

J. D. Fryer and S. A. Evans, "Weed Control Handbook", 5th Ed., Blackwell Scientific Publications, Oxford, 1968, pp. 101-103.

In the following examples, all parts are by weight unless otherwise indicated.

EXAMPLE 8 Wettable Powder

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                            50%                                               2-(2-oxiranylmethyl)benzenesulfonamide,                                        sodium alkylnaphthalenesulfonate                                                                            2%                                                low viscosity methyl cellulose                                                                              2%                                                diatomaceous earth           46%                                               ______________________________________                                    

The ingredients are blended, coarsely hammermilled and then air-milled to produce particles essentially all below 10 microns in diameter. The product is reblended before packaging.

EXAMPLE 9 Granule

    ______________________________________                                         Wettable Powder of Example 8                                                                             5%                                                   attapulgite granules      95%                                                  (U.S.S. 20-40 mesh; 0.84-0.42 mm)                                              ______________________________________                                    

A slurry of wettable powder containing 25% solids is sprayed on the surface of attapulgite granules in a double-cone blender. The granules are dried and packaged.

EXAMPLE 10 Extruded Pellet

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                            25%                                               2-(2-oxiranylmethyl)benzenesulfonamide                                         anhydrous sodium sulfate     10%                                               crude calcium ligninsulfonate                                                                               5%                                                sodium alkylnaphthalenesulfonate                                                                            1%                                                calcium/magnesium bentonite  59%                                               ______________________________________                                    

The ingredients are blended, hammer-milled and then moistened with about 12% water. The mixture is extruded as cylinders about 3 mm diameter which are cut to produce pellets about 3 mm long. These may be used directly after drying, or the dried pellets may be crushed to pass a U.S.S. No. 20 sieve (0.84 mm openings). The granules held on a U.S.S. No. 40 sieve (0.42 mm openings) may be packaged for use and the fines recycled.

EXAMPLE 11 Low Strength Granule

    ______________________________________                                         2-(2,2-dichlorocyclopropyl)-N--[(4-methoxy-6-methyl)-                                                       1%                                                aminocarbonyl]benzenesulfonamide                                               N,N--dimethylformamide       9%                                                attapulgite granules         90%                                               (U.S.S. 20-40 sieve)                                                           ______________________________________                                    

The active ingredient is dissolved in the solvent and the solution is sprayed upon dedusted granules in a double cone blender. After spraying of the solution has been completed, the blender is allowed to run for a short period and then the granules are packaged.

EXAMPLE 12 Aqueous Suspension

    ______________________________________                                         2-(2,2-dichlorocyclopropyl)-N--[(4-methoxy-6-methyl)-                                                      40%                                                aminocarbonyl]benzenesulfonamide                                               polyacrylic acid thickener  0.3%                                               dodecylphenol polyethylene glycol ether                                                                    0.5%                                               disodium phosphate          1%                                                 monosodium phosphate        0.5%                                               polyvinyl alcohol           1.0%                                               water                       56.7%                                              ______________________________________                                    

The ingredients are blended and ground together in a sand mill to produce particles essentially all under 5 microns in size.

EXAMPLE 13 Oil Suspension

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                            35%                                               2-(2-oxiranylmethyl)benzenesulfonamide                                         blend of polyalchol carboxylic                                                                              6%                                                esters and oil soluble petroleum                                               sulfonates                                                                     xylene                       59%                                               ______________________________________                                    

The ingredients are combined and ground together in a sand mill to produce particles essentially all below 5 microns. The product can be used directly, extended with oils, or emulsified in water.

EXAMPLE 14 Granule

    ______________________________________                                         2-(2,2-dichlorocyclopropyl)-N--[(4,6-dimethoxypyrimidin-                                                     80%                                              2-yl)aminocarbonyl]benzenesulfonamide                                          wetting agent                 1%                                               crude ligninsulfonate salt (containing                                                                       10%                                              5-20% of the natural sugars)                                                   attapulgite clay              9%                                               ______________________________________                                    

The ingredients are blended and milled to pass through a 100 mesh screen. This material is then added to a fluid bed granulator, the air flow is adjusted to gently fluidize the material, and a fine spray of water is sprayed onto the fluidized material. The fluidization and spraying are continued until granules of the desired size range are made The spraying is stopped, but fluidization is continued, optionally with heat, until the water content is reduced to the desired level, generally less than 1%. The material is then discharged, screened to the desired size range, generally 14-100 mesh (1410-149 microns), and packaged for use.

EXAMPLE 15 High Strength Concentrate

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                            99%                                               2-(2-oxiranylmethyl)benzenesulfonamide                                         silica aerogel               0.5%                                              synthetic amorphous silica   0.5%                                              ______________________________________                                    

The ingredients are blended and ground in a hammer-mill to produce a material essentially all passing a U.S.S. No. 50 screen (0.3 mm opening). The concentrate may be formulated further if necessary.

EXAMPLE 16 Wettable Powder

    ______________________________________                                         2-(2,2-dichlorocyclopropyl)-N--[(4-methoxy-6-methyl)-                                                       90%                                               aminocarbonyl]benzenesulfonamide                                               dioctyl sodium sulfosuccinate                                                                               0.1%                                              synthetic fine silica        9.9%                                              ______________________________________                                    

The ingredients are blended and ground in a hammer-mill to produce particles essentially all below 100 microns. The material is sifted through a U.S.S. No. 50 screen and then packaged.

EXAMPLE 17 Wettable Powder

    ______________________________________                                         2-(2,2-dichlorocyclopropyl)-N--[(4,6-dimethoxypyrimidin-                                                     40%                                              2-yl)aminocarbonyl]benzenesulfonamide                                          sodium ligninsulfonate        20%                                              montmorillonite clay          40%                                              ______________________________________                                    

The ingredients are thoroughly blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in size. The material is reblended and then packaged.

EXAMPLE 18 Dust

    ______________________________________                                         N--[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-                                                            10%                                               2-(2-oxiranylmethyl)benzenesulfonamide                                         attapulgite                  10%                                               Pyrophyllite                 80%                                               ______________________________________                                    

The active ingredient is blended with attapulgite and then passed through a hammer-mill to produce particles substantially all below 200 microns. The ground concentrate is then blended with powdered pyrophyllite until homogeneous.

Utility

Test results indicate that the compounds of the present invention are highly active preemergent or postemergent herbicides or plant growth regulants. Many of them have utility for broad-spectrum pre- and or post-emergence weed control in areas where complete control of all vegetation is desired, such as around fuel storage tanks, ammunition depots, industrial storage areas, parking lots, drive-in theaters, around billboards, highway and railroad structures. Some of the compounds have utility for selective weed control in crops such as rice and wheat. Alternatively, the subject compounds are useful to modify plant growth.

The rates of application for the compounds of the invention are determined by a number of factors, including their use as plant growth modifiers or as herbicides, the crop species involved, the types of weeds to be controlled, weather and climate, formulations selected, mode of application, amount of foilage present, etc. In general terms, the subject compounds should be applied at levels of arount 0.05 to 10 kg/ha, the lower rates being suggested for use on lighter soils and/or those having a low organic matter content, for plant growth modification or for situations where only short-term persistence is required.

The compounds of the invention may be used in combination with any other commercial herbicide, examples of which are those of the triazine, triazole, uracil, urea, amide, diphenylether, carbamate and bipyridylium types.

The herbicidal properties of the subject compounds were discovered in a number of greenhouse tests. The test procedures and results follow.

Test A

Seeds of crabgrass (Digitaria sp.), barnyardgrass (Echinochloa crusgalli), wild oats (Avena fatua), cheatgrass (Bromus secalinus), velvetleaf (Abutilon theophrasti), sicklepod (Cassia obtusifolia), morningglory (Ipomoea sp.), cocklebur (Xanthium sp.), sorghum, corn, soybean, rice, wheat and nutsedge tubers (Cyperus rotundus) were planted in a growth medium and treated pre-emergence with the chemicals dissolved in a nonphytotoxic solvent. At the same time, cotton having five leaves (including cotyledonary ones), bush beans with the third trifoliate leaf expanding, crabgrass, barnyardgrass and wild oats with two leaves, sicklepod with three leaves (including cotyledonary ones), morningglory and cocklebur with four leaves (including the cotyledonary ones), sorghum and corn with four leaves, soybean with two cotyledonary leaves, rice with three leaves, wheat with one leaf, and nutsedge with three to five leaves were sprayed. Treated plants and controls were maintained in a greenhouse for sixteen days, whereupon all species were compared to controls and visually rated for response to treatment. The ratings are based on a numerical scale extending from 0=no injury, to 10=complete kill. The accompanying descriptive symbols have the following meanings:

C=chlorosis or necrosis;

B=burn;

D=defoliation;

E=emergence inhibition;

G=growth retardation;

H=formative effects;

U=unusual pigmentation

X=axillary stimulation;

S=albinism; and

6Y=abscised buds or flowers.

    ______________________________________                                         Compounds                                                                       ##STR49##                                                                     Compound                                                                               n     Q               X     Y     Z                                    ______________________________________                                         1       0     2,2-dichlorocyclopropyl                                                                        CH.sub.3                                                                             CH.sub.3                                                                             CH                                   2       0     2,2-dichlorocyclopropyl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                            CH                                   3       0     2,2-dichlorocyclopropyl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                   4       0     2,2-dichlorocyclopropyl                                                                        CH.sub.3                                                                             CH.sub.3                                                                             N                                    5       0     2,2-dichlorocyclopropyl                                                                        CH.sub.3                                                                             OCH.sub.3                                                                            N                                    6       0     2,2-dichlorocyclopropyl                                                                        OCH.sub.3                                                                            OCH.sub.3                                                                            N                                    7       1                                                                                     ##STR50##      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                   8       0                                                                                     ##STR51##      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                   9       0                                                                                     ##STR52##      CH.sub.3                                                                             CH.sub.3                                                                             CH                                   ______________________________________                                    

                                      TABLE A                                      __________________________________________________________________________             Compound 1                                                                            Compound 2                                                                            Compound 3                                                                            Compound 4                                                                            Compound 5                                 Rate (kg/ha)                                                                           0.05   0.05   0.05   0.05   0.05                                       __________________________________________________________________________     POSTEMERGENCE                                                                  Morningglory                                                                           0      2C,5G  5C,8G  4C,8G  10C                                        Cocklebur                                                                              5G     9C     9C     3C,8G  9C                                         Velvetleaf                                                                             2C,8G  9C     10C    4C,8H  10C                                        Nutsedge                                                                               0      10C    9C     0      9C                                         Crabgrass                                                                              0      2G     4G     0      2G                                         Barnyardgrass                                                                          0      8H     3H     0      2H                                         Cheatgrass                                                                             0      2C,6G  2C,6G  0      2C                                         Wild Oats                                                                              0      2G     0      0      0                                          Wheat   0      0      0      0      3G                                         Corn    0      2C,8H  1C,4G  0      3C,8H                                      Soybean 2C,9G  4C,9G  5C,9G  2C,9G  3C,9G                                      Rice    5G     2C,7G  2C,6G  3G     5G                                         Sorghum 2H     2G     2G     0      2C,5H                                      Sugar Beets                                                                            0      5G     4C,8G  5C,9G  9C                                         Cotton  4C,8H  5C,9G  5C,9G  4C,8H  5C,9G                                      Bushbean                                                                       Cassia                                                                         PREEMERGENCE                                                                   Morningglory                                                                           4G     8G     7G     7H     9G                                         Cocklebur                                                                              --     8H     9G     2C     9H                                         Velvetleaf                                                                             2G     9G     9G     0      9G                                         Nutsedge                                                                               0      9G     10E    0      4G                                         Crabgrass                                                                              0      2G     2C,8G  0      0                                          Barnyardgrass                                                                          0      2C,9H  2C,7H  0      2C,3H                                      Cheatgrass                                                                             2G     5C,9H  5C,9H  0      5G                                         Wild Oats                                                                              0      3C,8G  3G     0      2G                                         Wheat   0      6G     2G     0      0                                          Corn    2G     2C,9H  2C,8G  2G     4G                                         Soybean 0      4C,8H  7G     3C,2H  4C,8H                                      Rice    3G     4C,8G  2C,8H  0      4G                                         Sorghum 5G     4C,8H  2C,7H  0      2C,5G                                      Sugar Beets                                                                            5G     8G     9G     3C,5G  10E                                        Cotton  5G     9G     8G     5G     9G                                         Bushbean                                                                       Cassia                                                                         __________________________________________________________________________             Compound 6                                                                              Compound 7                                                                              Compound 8                                                                             Compound 9                                   Rate (kg/ha)                                                                           0.05     0.05     0.05    0.05                                         __________________________________________________________________________     POSTEMERGENCE                                                                  Morningglory                                                                           10C      2C,8G    1C      0                                            Cocklebur                                                                              10C      8H       2C,7G   2G                                           Velvetleaf                                                                             10C      --       9C      2G                                           Nutsedge                                                                               9C       10C      4C,9G   1C                                           Crabgrass                                                                              0        1C,5G    1C      0                                            Barnyardgrass                                                                          0        5C,9H    4C,9H   2C,4H                                        Cheatgrass                                                                             1C       --       3G      0                                            Wild Oats                                                                              0        2G       0       0                                            Wheat   0        2G       0       0                                            Corn    3C,8H    2C,8H    2C,7H   2C,5G                                        Soybean 4C,9G    4C,8H    3C,9G,7X                                                                               2C,2H                                        Rice    3G       4C,9G    6G      3G                                           Sorghum 2C,5H    2C,9H    2C,7H   2C,5G                                        Sugar Beets                                                                            10C      9C       9C      2C,5G                                        Cotton  9C       4C,4H    9C      1H                                           Bushbean         5C,9G    --      --                                           Cassia           2C,9G    --      --                                           PREEMERGENCE                                                                   Morningglory                                                                           8G       7G       5G      0                                            Cocklebur                                                                              9C       9H       0       0                                            Velvetleaf                                                                             5C,9G    --       0       0                                            Nutsedge                                                                               7G       5G       0       0                                            Crabgrass                                                                              0        2C       0       0                                            Barnyardgrass                                                                          2C       4C,8H    0       0                                            Cheatgrass                                                                             0        --       0       0                                            Wild Oats                                                                              0        3C,6G    0       0                                            Wheat   0        1C,3G    0       0                                            Corn    2C,6G    2C,8H    0       1H                                           Soybean 3C,8H    2C,8H    2C      1H                                           Rice    3G       3C,8G    0       4G                                           Sorghum 2G       3C,9G    1C      2G                                           Sugar Beets                                                                            5C,9G    9G       6G      2H                                           Cotton  9G       --       2G      0                                            Bushbean         --       --      --                                           Cassia           5C,9H    --      --                                           __________________________________________________________________________ 

What is claimed is:
 1. A compound of the formula ##STR53## wherein W is O or S;R is H or CH₃ ; L is ##STR54## n is 0 or 1; R₁ is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, nitro, CN, C₁ -C₃ alkoxy, SO₂ NR^(I) R^(II), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, CO₂ R^(III), CH₂ CN, CH₂ OCH₃ or CH₂ SCH₃ ; R^(I) is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy or ethoxy; R^(II) is H, C₁ -C₄ alkyl or C₃ -C₄ alkenyl; or R^(I) and R^(II) may be taken together as --(CH₂)₃ --, --(CH₂)₄ --, --(CH₂)₅ -- or --CH₂ CH₂ OCH₂ CH₂ --; R^(III) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₃ cyanoalkyl, C₅ -C₆ cycloalkyl, C₄ -C₇ cycloalkylalkyl or C₂ -C₄ alkoxyalkyl; R₂ is C₁ -C₃ alkyl; Q is a 3- or 4-membered heterocyclic ring which contains one heteroatom selected from O, S and NR₃, or a 3- or 4-membered carbocyclic ring in which one carbon atom may optionally be in the form of a carbonyl group, or a fully-saturated 5- or 6-membered carbocyclic ring, and Q may be optionally substituted with 1-4 substituents selected from halogen, CN, OH, C₁ -C₃ alkyl, C₁ -C₃ alkoxy, C₁ -C₃ alkylthio, C₂ -C₄ alkoxycarbonyl, C₁ -C₄ alkylsulfonyl, (C₁ -C₄ alkyl)-aminosulfamoyl and di(C₁ -C₄ alkyl)aminosulfamoyl; R₃ is C₁ -C₄ alkyl; R₁₂ is H or OR₁₄ ; R₁₃ is H or C₁ -C₄ alkyl; R₁₄ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ haloalkenyl, C₃ -C₄ alkynyl, C₃ -C₄ haloalkynyl, C₂ -C₄ alkylcarbonyl, C(O)NR₁₅ R₁₆, C₁ -C₄ alkylsulfonyl, C₂ -C₄ alkoxyalkyl or C₂ -C₄ alkylthioalkyl; R₁₅ and R₁₆ are independently H or C₁ -C₂ alkyl; A is ##STR55## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃ alkyl)amino; Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₃ -C₅ cycloalkyl, C₂ -C₄ alkynyl, ##STR56## or N(OCH₃)CH₃ ; m is 2 or 3; L₁ and L₂ are independently O or S; R₄ and R₅ are independently C₁ -C₂ alkyl; R₆ is H or CH₃ ;and their agriculturally suitable salts; provided that (a) when X is Cl, F, Br or I, then Y is OCH₃, OC₂ H₅, N(OCH₃)CH₃, NHCH₃, N(CH₃)₂ or OCF₂ H; (b) when L is L-2 or L-3, then the Q substituent and the sulfonylurea bridge are on adjacent carbon atoms; (c) when W is S, then R is H, and Y is CH₃, OCH₃, OC₂ H, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ .tbd.CH, OCH₂ CH₂ OCH₃ or CH(OCH₃)₂ ; (d) the total number of carbon atoms of R₁₂ and R₁₃ must be less than or equal to four; and (e) when the total number of carbon atoms of X and Y is greater than four, then the number of carbons of R₁ must be less than or equal to two and the number of carbons of Q must be less than or equal to six.
 2. The compounds of claim 1 wherein Q is ##STR57## wherein R₃ is C₁ -C₃ alkyl;R₇ is H, F, Cl, Br, CN, CH₃ or OCH₃ ; R₈ is H, F, Cl, Br, I, CN, OH, C₁ -C₃ alkyl, C₁ -C₃ alkoxy, C₂ -C₃ alkoxycarbonyl, di(C₁ -C₃ alkyl)aminosulfamoyl, C₁ -C₃ alkylthio or C₁ -C₃ alkylsulfonyl; R₉ and R₁₀ are independently H, CH₃, F, Cl or may be taken together to form C═O; and R₁₁ is H or C₁ -C₃ alkyl;provided that (a) when R₇ and R₈ are attached to the same carbon atom as in Q-1, Q-2 or Q-3, or in Q-4 through Q-10, and R₇ is OCH₃, then R₈ is other than F, Cl, Br, I or OH; and (b) when R₇ and R₈ are attached to the same carbon atom as in Q-1, Q-2 or Q-3, or in Q-4 through Q-10, and R₈ is F, Cl, Br, I or OH, then R₇ is other than OCH₃.
 3. The compounds of claim 2 whereW is O; and R is H.
 4. The compounds of claim 3 whereR₁ is selected from H, F, Cl, NO₂, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, C₁ -C₂ alkoxy, C₁ -C₂ alkylthio, CH₂ OCH₃ or CH₂ SCH₃ ; R₁₃ is H or CH₃ ; R₁₄ is H, C₁ -C₂ alkyl, CH₂ CH═CH₂ or CH₂ C.tbd.CH; X is CH₃, OCH₃, OC₂ H₅, Cl, F, Br, OCF₂ H, CH₂ F, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CF₃, CH₂ Cl or CH₂ Br; and Y is H, C₁ -C₃ alkyl, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OC₂ H₅, OCH₂ CH₂ OCH₃, CH₂ SCH₃, OCF₂ H, SCF₂ H, cyclopropyl, C.tbd.CH or C.tbd.CCH₃.
 5. The compounds of claim 4 whereL is L-1; and Q is Q-1, Q-2 or Q-4.
 6. The compounds of claim 5 where Q is Q-1;
 7. The compounds of claim 6 whereR₁ is H, Cl, CH₃, OCH₃ or SCH₃ and is not in the 4-position; R₇ is H, F, Cl, CH₃ or OCH₃ ; R₈ is H, F, Cl, CH₃ or OCH₃ ; and R₉ and R₁₀ are independently H, CH₃, F or Cl.
 8. The compound of claim 1 which is 2-(2,2-dichlorocyclopropyl)-N-[(4,6-dimethoxypyrimidin-2-yl)-aminocarbonyl]benzenesulfonamide.
 9. The compound of claim 1 which is N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranylmethyl)benzenesulfonamide.
 10. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 1 and at least one of the following: surfactant, solid or liquid diluent.
 11. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 2 and at least one of the following: surfactant, solid or liquid diluent.
 12. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 3 and at least one of the following: surfactant, solid or liquid diluent.
 13. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 4 and at least one of the following: surfactant, solid or liquid diluent.
 14. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 5 and at least one of the following: surfactant, solid or liquid diluent.
 15. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 6 and at least one of the following: surfactant, solid or liquid diluent.
 16. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 7 and at least one of the following: surfactant, solid or liquid diluent.
 17. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 8 and at least one of the following: surfactant, solid or liquid diluent.
 18. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 9 and at least one of the following: surfactant, solid or liquid diluent.
 19. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 1. 20. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 2. 21. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 3. 22. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 4. 23. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 5. 24. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 6. 25. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 7. 26. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 8. 27. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 9. 